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Bioactive Flavonoids and Catechols as Hif1 and Nrf2 Protein Stabilizers - Implications for Parkinson's Disease.
Smirnova NA, Kaidery NA, Hushpulian DM, Rakhman II, Poloznikov AA, Tishkov VI, Karuppagounder SS, Gaisina IN, Pekcec A, Leyen KV, Kazakov SV, Yang L, Thomas B, Ratan RR, Gazaryan IG. Smirnova NA, et al. Among authors: pekcec a. Aging Dis. 2016 Dec 1;7(6):745-762. doi: 10.14336/AD.2016.0505. eCollection 2016 Dec. Aging Dis. 2016. PMID: 28053825 Free PMC article.
Inhibition of 12/15-lipoxygenase as therapeutic strategy to treat stroke.
Yigitkanli K, Pekcec A, Karatas H, Pallast S, Mandeville E, Joshi N, Smirnova N, Gazaryan I, Ratan RR, Witztum JL, Montaner J, Holman TR, Lo EH, van Leyen K. Yigitkanli K, et al. Among authors: pekcec a. Ann Neurol. 2013 Jan;73(1):129-35. doi: 10.1002/ana.23734. Epub 2012 Nov 28. Ann Neurol. 2013. PMID: 23192915 Free PMC article.
Inhibition of human microsomal PGE2 synthase-1 reduces seizure-induced increases of P-glycoprotein expression and activity at the blood-brain barrier.
Soldner ELB, Hartz AMS, Akanuma SI, Pekcec A, Doods H, Kryscio RJ, Hosoya KI, Bauer B. Soldner ELB, et al. Among authors: pekcec a. FASEB J. 2019 Dec;33(12):13966-13981. doi: 10.1096/fj.201901460RR. Epub 2019 Oct 22. FASEB J. 2019. PMID: 31638830 Free PMC article.
To test our hypothesis, we exposed isolated brain capillaries to glutamate ex vivo and used a combined in vivo-ex vivo approach by isolating brain capillaries from humanized mPGES-1 mice to study P-gp levels. ...Our data provide key signaling steps underlying seizure-induc …
To test our hypothesis, we exposed isolated brain capillaries to glutamate ex vivo and used a combined in vivo-ex vivo approach by is …
52 results