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Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity.
Soethoudt M, Grether U, Fingerle J, Grim TW, Fezza F, de Petrocellis L, Ullmer C, Rothenhäusler B, Perret C, van Gils N, Finlay D, MacDonald C, Chicca A, Gens MD, Stuart J, de Vries H, Mastrangelo N, Xia L, Alachouzos G, Baggelaar MP, Martella A, Mock ED, Deng H, Heitman LH, Connor M, Di Marzo V, Gertsch J, Lichtman AH, Maccarrone M, Pacher P, Glass M, van der Stelt M. Soethoudt M, et al. Among authors: maccarrone m. Nat Commun. 2017 Jan 3;8:13958. doi: 10.1038/ncomms13958. Nat Commun. 2017. PMID: 28045021 Free PMC article.
Anandamide hydrolysis by human cells in culture and brain.
Maccarrone M, van der Stelt M, Rossi A, Veldink GA, Vliegenthart JF, Agrò AF. Maccarrone M, et al. J Biol Chem. 1998 Nov 27;273(48):32332-9. doi: 10.1074/jbc.273.48.32332. J Biol Chem. 1998. PMID: 9822713 Free article.
Oxygenated metabolites of anandamide and 2-arachidonoylglycerol: conformational analysis and interaction with cannabinoid receptors, membrane transporter, and fatty acid amide hydrolase.
van der Stelt M, van Kuik JA, Bari M, van Zadelhoff G, Leeflang BR, Veldink GA, Finazzi-Agrò A, Vliegenthart JF, Maccarrone M. van der Stelt M, et al. Among authors: maccarrone m. J Med Chem. 2002 Aug 15;45(17):3709-20. doi: 10.1021/jm020818q. J Med Chem. 2002. PMID: 12166944
Acute neuronal injury, excitotoxicity, and the endocannabinoid system.
van der Stelt M, Veldhuis WB, Maccarrone M, Bär PR, Nicolay K, Veldink GA, Di Marzo V, Vliegenthart JF. van der Stelt M, et al. Among authors: maccarrone m. Mol Neurobiol. 2002 Oct-Dec;26(2-3):317-46. doi: 10.1385/MN:26:2-3:317. Mol Neurobiol. 2002. PMID: 12428763 Review.
Neuroprotection by the endogenous cannabinoid anandamide and arvanil against in vivo excitotoxicity in the rat: role of vanilloid receptors and lipoxygenases.
Veldhuis WB, van der Stelt M, Wadman MW, van Zadelhoff G, Maccarrone M, Fezza F, Veldink GA, Vliegenthart JF, Bär PR, Nicolay K, Di Marzo V. Veldhuis WB, et al. Among authors: maccarrone m. J Neurosci. 2003 May 15;23(10):4127-33. doi: 10.1523/JNEUROSCI.23-10-04127.2003. J Neurosci. 2003. PMID: 12764100 Free PMC article.
545 results