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Imine reductases (IREDs).
Mangas-Sanchez J, France SP, Montgomery SL, Aleku GA, Man H, Sharma M, Ramsden JI, Grogan G, Turner NJ. Mangas-Sanchez J, et al. Curr Opin Chem Biol. 2017 Apr;37:19-25. doi: 10.1016/j.cbpa.2016.11.022. Epub 2016 Dec 27. Curr Opin Chem Biol. 2017. PMID: 28038349 Free article. Review.
Structures of a γ-aminobutyrate (GABA) transaminase from the s-triazine-degrading organism Arthrobacter aurescens TC1 in complex with PLP and with its external aldimine PLP-GABA adduct.
Bruce H, Nguyen Tuan A, Mangas Sánchez J, Leese C, Hopwood J, Hyde R, Hart S, Turkenburg JP, Grogan G. Bruce H, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Oct 1;68(Pt 10):1175-80. doi: 10.1107/S1744309112030023. Epub 2012 Sep 29. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012. PMID: 23027742 Free PMC article.
A reductive aminase from Aspergillus oryzae.
Aleku GA, France SP, Man H, Mangas-Sanchez J, Montgomery SL, Sharma M, Leipold F, Hussain S, Grogan G, Turner NJ. Aleku GA, et al. Nat Chem. 2017 Oct;9(10):961-969. doi: 10.1038/nchem.2782. Epub 2017 May 29. Nat Chem. 2017. PMID: 28937665
Biocatalytic Routes to Enantiomerically Enriched Dibenz[c,e]azepines.
France SP, Aleku GA, Sharma M, Mangas-Sanchez J, Howard RM, Steflik J, Kumar R, Adams RW, Slabu I, Crook R, Grogan G, Wallace TW, Turner NJ. France SP, et al. Angew Chem Int Ed Engl. 2017 Dec 4;56(49):15589-15593. doi: 10.1002/anie.201708453. Epub 2017 Nov 7. Angew Chem Int Ed Engl. 2017. PMID: 29024400 Free article.
26 results