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Developing anti-neoplastic biotherapeutics against eIF4F.
Steinberger J, Chu J, Maïga RI, Sleiman K, Pelletier J. Steinberger J, et al. Among authors: chu j. Cell Mol Life Sci. 2017 May;74(9):1681-1692. doi: 10.1007/s00018-016-2430-8. Epub 2016 Dec 21. Cell Mol Life Sci. 2017. PMID: 28004147 Free PMC article. Review.
Therapeutic Opportunities in Eukaryotic Translation.
Chu J, Pelletier J. Chu J, et al. Cold Spring Harb Perspect Biol. 2018 Jun 1;10(6):a032995. doi: 10.1101/cshperspect.a032995. Cold Spring Harb Perspect Biol. 2018. PMID: 29440069 Free PMC article. Review.
Oxo-aglaiastatin-Mediated Inhibition of Translation Initiation.
Itoua Maïga R, Cencic R, Chu J, Waller DD, Brown LE, Devine WG, Zhang W, Sebag M, Porco JA Jr, Pelletier J. Itoua Maïga R, et al. Among authors: chu j. Sci Rep. 2019 Feb 4;9(1):1265. doi: 10.1038/s41598-018-37666-5. Sci Rep. 2019. PMID: 30718665 Free PMC article.
Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F.
Chu J, Zhang W, Cencic R, O'Connor PBF, Robert F, Devine WG, Selznick A, Henkel T, Merrick WC, Brown LE, Baranov PV, Porco JA Jr, Pelletier J. Chu J, et al. Cell Rep. 2020 Feb 25;30(8):2481-2488.e5. doi: 10.1016/j.celrep.2020.02.002. Cell Rep. 2020. PMID: 32101697 Free PMC article.
Identification and characterization of hippuristanol-resistant mutants reveals eIF4A1 dependencies within mRNA 5' leader regions.
Steinberger J, Shen L, J Kiniry S, Naineni SK, Cencic R, Amiri M, Aboushawareb SAE, Chu J, Maïga RI, Yachnin BJ, Robert F, Sonenberg N, Baranov PV, Pelletier J. Steinberger J, et al. Among authors: j kiniry s, chu j. Nucleic Acids Res. 2020 Sep 25;48(17):9521-9537. doi: 10.1093/nar/gkaa662. Nucleic Acids Res. 2020. PMID: 32766783 Free PMC article.
5,202 results