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Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis.
Van Welden S, De Vos M, Wielockx B, Tavernier SJ, Dullaers M, Neyt S, Descamps B, Devisscher L, Devriese S, Van den Bossche L, Holvoet T, Baeyens A, Correale C, D'Alessio S, Vanhove C, De Vos F, Verhasselt B, Breier G, Lambrecht BN, Janssens S, Carmeliet P, Danese S, Elewaut D, Laukens D, Hindryckx P. Van Welden S, et al. Among authors: holvoet t. J Pathol. 2017 Mar;241(4):547-558. doi: 10.1002/path.4861. Epub 2017 Jan 27. J Pathol. 2017. PMID: 27981571
Ursodeoxycholic Acid and Its Taurine- or Glycine-Conjugated Species Reduce Colitogenic Dysbiosis and Equally Suppress Experimental Colitis in Mice.
Van den Bossche L, Hindryckx P, Devisscher L, Devriese S, Van Welden S, Holvoet T, Vilchez-Vargas R, Vital M, Pieper DH, Vanden Bussche J, Vanhaecke L, Van de Wiele T, De Vos M, Laukens D. Van den Bossche L, et al. Among authors: holvoet t. Appl Environ Microbiol. 2017 Mar 17;83(7):e02766-16. doi: 10.1128/AEM.02766-16. Print 2017 Apr 1. Appl Environ Microbiol. 2017. PMID: 28115375 Free PMC article.
T84 monolayers are superior to Caco-2 as a model system of colonocytes.
Devriese S, Van den Bossche L, Van Welden S, Holvoet T, Pinheiro I, Hindryckx P, De Vos M, Laukens D. Devriese S, et al. Among authors: holvoet t. Histochem Cell Biol. 2017 Jul;148(1):85-93. doi: 10.1007/s00418-017-1539-7. Epub 2017 Mar 6. Histochem Cell Biol. 2017. PMID: 28265783
Treatment of Intestinal Fibrosis in Experimental Inflammatory Bowel Disease by the Pleiotropic Actions of a Local Rho Kinase Inhibitor.
Holvoet T, Devriese S, Castermans K, Boland S, Leysen D, Vandewynckel YP, Devisscher L, Van den Bossche L, Van Welden S, Dullaers M, Vandenbroucke RE, De Rycke R, Geboes K, Bourin A, Defert O, Hindryckx P, De Vos M, Laukens D. Holvoet T, et al. Gastroenterology. 2017 Oct;153(4):1054-1067. doi: 10.1053/j.gastro.2017.06.013. Epub 2017 Jun 19. Gastroenterology. 2017. PMID: 28642198
Fecal Microbiota Transplantation Reduces Symptoms in Some Patients With Irritable Bowel Syndrome With Predominant Abdominal Bloating: Short- and Long-term Results From a Placebo-Controlled Randomized Trial.
Holvoet T, Joossens M, Vázquez-Castellanos JF, Christiaens E, Heyerick L, Boelens J, Verhasselt B, van Vlierberghe H, De Vos M, Raes J, De Looze D. Holvoet T, et al. Gastroenterology. 2021 Jan;160(1):145-157.e8. doi: 10.1053/j.gastro.2020.07.013. Epub 2020 Jul 15. Gastroenterology. 2021. PMID: 32681922 Clinical Trial.
Efficacy of vedolizumab for induction of clinical response and remission in patients with moderate to severe inflammatory bowel disease who failed at least two TNF antagonists.
De Vos M, Dhooghe B, Vermeire S, Louis E, Mana F, Elewaut A, Bossuyt P, Baert F, Reenaers C, Van Gossum M, Macken E, Ferrante M, Hindryckx P, Dewit O, Holvoet T, Franchimont D; Belgian Inflammatory Bowel Disease Research and Development (BIRD). De Vos M, et al. Among authors: holvoet t. United European Gastroenterol J. 2018 Apr;6(3):439-445. doi: 10.1177/2050640617722310. Epub 2017 Jul 26. United European Gastroenterol J. 2018. PMID: 29774158 Free PMC article.
25 results