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The Study of Posttranslational Modifications of Tau Protein by Nuclear Magnetic Resonance Spectroscopy: Phosphorylation of Tau Protein by ERK2 Recombinant Kinase and Rat Brain Extract, and Acetylation by Recombinant Creb-Binding Protein.
Qi H, Despres C, Prabakaran S, Cantrelle FX, Chambraud B, Gunawardena J, Lippens G, Smet-Nocca C, Landrieu I. Qi H, et al. Among authors: chambraud b. Methods Mol Biol. 2017;1523:179-213. doi: 10.1007/978-1-4939-6598-4_11. Methods Mol Biol. 2017. PMID: 27975251
Immunophilin FKBP52 induces Tau-P301L filamentous assembly in vitro and modulates its activity in a model of tauopathy.
Giustiniani J, Chambraud B, Sardin E, Dounane O, Guillemeau K, Nakatani H, Paquet D, Kamah A, Landrieu I, Lippens G, Baulieu EE, Tawk M. Giustiniani J, et al. Among authors: chambraud b. Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4584-9. doi: 10.1073/pnas.1402645111. Epub 2014 Mar 12. Proc Natl Acad Sci U S A. 2014. PMID: 24623856 Free PMC article.
A β-Turn Motif in the Steroid Hormone Receptor's Ligand-Binding Domains Interacts with the Peptidyl-prolyl Isomerase (PPIase) Catalytic Site of the Immunophilin FKBP52.
Byrne C, Henen MA, Belnou M, Cantrelle FX, Kamah A, Qi H, Giustiniani J, Chambraud B, Baulieu EE, Lippens G, Landrieu I, Jacquot Y. Byrne C, et al. Among authors: chambraud b. Biochemistry. 2016 Sep 27;55(38):5366-76. doi: 10.1021/acs.biochem.6b00506. Epub 2016 Sep 19. Biochemistry. 2016. PMID: 27641460
Identification of the Tau phosphorylation pattern that drives its aggregation.
Despres C, Byrne C, Qi H, Cantrelle FX, Huvent I, Chambraud B, Baulieu EE, Jacquot Y, Landrieu I, Lippens G, Smet-Nocca C. Despres C, et al. Among authors: chambraud b. Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):9080-9085. doi: 10.1073/pnas.1708448114. Epub 2017 Aug 7. Proc Natl Acad Sci U S A. 2017. PMID: 28784767 Free PMC article.
Major Differences between the Self-Assembly and Seeding Behavior of Heparin-Induced and in Vitro Phosphorylated Tau and Their Modulation by Potential Inhibitors.
Despres C, Di J, Cantrelle FX, Li Z, Huvent I, Chambraud B, Zhao J, Chen J, Chen S, Lippens G, Zhang F, Linhardt R, Wang C, Klärner FG, Schrader T, Landrieu I, Bitan G, Smet-Nocca C. Despres C, et al. Among authors: chambraud b. ACS Chem Biol. 2019 Jun 21;14(6):1363-1379. doi: 10.1021/acschembio.9b00325. Epub 2019 May 15. ACS Chem Biol. 2019. PMID: 31046227 Free PMC article.
A role for FKBP52 in Tau protein function.
Chambraud B, Sardin E, Giustiniani J, Dounane O, Schumacher M, Goedert M, Baulieu EE. Chambraud B, et al. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2658-63. doi: 10.1073/pnas.0914957107. Epub 2010 Jan 25. Proc Natl Acad Sci U S A. 2010. PMID: 20133804 Free PMC article.
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