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Discovery of a 1-Methyl-3,4-dihydronaphthalene-Based Sphingosine-1-Phosphate (S1P) Receptor Agonist Ceralifimod (ONO-4641). A S1P1 and S1P5 Selective Agonist for the Treatment of Autoimmune Diseases.
Kurata H, Kusumi K, Otsuki K, Suzuki R, Kurono M, Komiya T, Hagiya H, Mizuno H, Shioya H, Ono T, Takada Y, Maeda T, Matsunaga N, Kondo T, Tominaga S, Nunoya KI, Kiyoshi H, Komeno M, Nakade S, Habashita H. Kurata H, et al. Among authors: shioya h. J Med Chem. 2017 Dec 14;60(23):9508-9530. doi: 10.1021/acs.jmedchem.7b00785. Epub 2017 Nov 21. J Med Chem. 2017. PMID: 29120624
Efficacy and immunomodulatory actions of ONO-4641, a novel selective agonist for sphingosine 1-phosphate receptors 1 and 5, in preclinical models of multiple sclerosis.
Komiya T, Sato K, Shioya H, Inagaki Y, Hagiya H, Kozaki R, Imai M, Takada Y, Maeda T, Kurata H, Kurono M, Suzuki R, Otsuki K, Habashita H, Nakade S. Komiya T, et al. Among authors: shioya h. Clin Exp Immunol. 2013 Jan;171(1):54-62. doi: 10.1111/j.1365-2249.2012.04669.x. Clin Exp Immunol. 2013. PMID: 23199323 Free PMC article.
Discovery of S1P agonists with a dihydronaphthalene scaffold.
Kurata H, Kusumi K, Otsuki K, Suzuki R, Kurono M, Takada Y, Shioya H, Komiya T, Mizuno H, Ono T, Hagiya H, Minami M, Nakade S, Habashita H. Kurata H, et al. Among authors: shioya h. Bioorg Med Chem Lett. 2011 Jul 1;21(13):3885-9. doi: 10.1016/j.bmcl.2011.05.029. Epub 2011 May 15. Bioorg Med Chem Lett. 2011. PMID: 21641216
Structure-activity relationship studies of S1P agonists with a dihydronaphthalene scaffold.
Kurata H, Kusumi K, Otsuki K, Suzuki R, Kurono M, Tokuda N, Takada Y, Shioya H, Mizuno H, Komiya T, Ono T, Hagiya H, Minami M, Nakade S, Habashita H. Kurata H, et al. Among authors: shioya h. Bioorg Med Chem Lett. 2012 Jan 1;22(1):144-8. doi: 10.1016/j.bmcl.2011.11.048. Epub 2011 Nov 20. Bioorg Med Chem Lett. 2012. PMID: 22153936
Straining graphene using thin film shrinkage methods.
Shioya H, Craciun MF, Russo S, Yamamoto M, Tarucha S. Shioya H, et al. Nano Lett. 2014 Mar 12;14(3):1158-63. doi: 10.1021/nl403679f. Epub 2014 Feb 3. Nano Lett. 2014. PMID: 24490629 Free PMC article.
Electron States of Uniaxially Strained Graphene.
Shioya H, Russo S, Yamamoto M, Craciun MF, Tarucha S. Shioya H, et al. Nano Lett. 2015 Dec 9;15(12):7943-8. doi: 10.1021/acs.nanolett.5b03027. Epub 2015 Nov 30. Nano Lett. 2015. PMID: 26619326
Lung sound analysis for predicting recurrent wheezing in preschool children.
Miyamoto M, Yoshihara S, Shioya H, Tadaki H, Imamura T, Enseki M, Furuya H, Kato M, Mochizuki H. Miyamoto M, et al. Among authors: shioya h. J Allergy Clin Immunol Glob. 2023 Dec 7;3(1):100199. doi: 10.1016/j.jacig.2023.100199. eCollection 2024 Feb. J Allergy Clin Immunol Glob. 2023. PMID: 38261936 Free PMC article.
79 results