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Monoaminergic and Histaminergic Strategies and Treatments in Brain Diseases.
Di Giovanni G, Svob Strac D, Sole M, Unzeta M, Tipton KF, Mück-Šeler D, Bolea I, Della Corte L, Nikolac Perkovic M, Pivac N, Smolders IJ, Stasiak A, Fogel WA, De Deurwaerdère P. Di Giovanni G, et al. Among authors: bolea i. Front Neurosci. 2016 Nov 24;10:541. doi: 10.3389/fnins.2016.00541. eCollection 2016. Front Neurosci. 2016. PMID: 27932945 Free PMC article. Review.
Multi-Target Directed Donepezil-Like Ligands for Alzheimer's Disease.
Unzeta M, Esteban G, Bolea I, Fogel WA, Ramsay RR, Youdim MB, Tipton KF, Marco-Contelles J. Unzeta M, et al. Among authors: bolea i. Front Neurosci. 2016 May 25;10:205. doi: 10.3389/fnins.2016.00205. eCollection 2016. Front Neurosci. 2016. PMID: 27252617 Free PMC article. Review.
A therapeutic approach to cerebrovascular diseases based on indole substituted hydrazides and hydrazines able to interact with human vascular adhesion protein-1, monoamine oxidases (A and B), AChE and BuChE.
Esteban G, Bolea I, Sun P, Solé M, Samadi A, Marco-Contelles J, Unzeta M. Esteban G, et al. Among authors: bolea i. J Neural Transm (Vienna). 2013 Jun;120(6):911-8. doi: 10.1007/s00702-012-0949-x. Epub 2012 Dec 21. J Neural Transm (Vienna). 2013. PMID: 23263540
Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
Bolea I, Juárez-Jiménez J, de Los Ríos C, Chioua M, Pouplana R, Luque FJ, Unzeta M, Marco-Contelles J, Samadi A. Bolea I, et al. J Med Chem. 2011 Dec 22;54(24):8251-70. doi: 10.1021/jm200853t. Epub 2011 Nov 15. J Med Chem. 2011. PMID: 22023459
20 results