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Discovery of a new isomannide-based peptidomimetic synthetized by Ugi multicomponent reaction as human tissue kallikrein 1 inhibitor.
Barros TG, Santos JAN, de Souza BEG, Sodero ACR, de Souza AMT, da Silva DP, Rodrigues CR, Pinheiro S, Dias LRS, Abrahim-Vieira B, Puzer L, Muri EMF. Barros TG, et al. Among authors: de souza amt, de souza beg. Bioorg Med Chem Lett. 2017 Jan 15;27(2):314-318. doi: 10.1016/j.bmcl.2016.11.051. Epub 2016 Nov 18. Bioorg Med Chem Lett. 2017. PMID: 27914800
Synthesis and mechanistic evaluation of novel N'-benzylidene-carbohydrazide-1H-pyrazolo[3,4-b]pyridine derivatives as non-anionic antiplatelet agents.
Lourenço AL, Salvador RRS, Silva LA, Saito MS, Mello JFR, Cabral LM, Rodrigues CR, Vera MAF, Muri EMF, de Souza AMT, Craik CS, Dias LRS, Castro HC, Sathler PC. Lourenço AL, et al. Among authors: de souza amt. Eur J Med Chem. 2017 Jul 28;135:213-229. doi: 10.1016/j.ejmech.2017.04.023. Epub 2017 Apr 14. Eur J Med Chem. 2017. PMID: 28453995
Synthesis and anticancer activities of some novel 2-(benzo[d]thiazol-2-yl)-8-substituted-2H-pyrazolo[4,3-c]quinolin-3(5H)-ones.
Reis Rda R, Azevedo EC, de Souza MC, Ferreira VF, Montenegro RC, Araújo AJ, Pessoa C, Costa-Lotufo LV, de Moraes MO, Filho JD, de Souza AM, de Carvalho NC, Castro HC, Rodrigues CR, Vasconcelos TR. Reis Rda R, et al. Eur J Med Chem. 2011 Apr;46(4):1448-52. doi: 10.1016/j.ejmech.2011.01.066. Epub 2011 Feb 3. Eur J Med Chem. 2011. PMID: 21334795
Synthesis, biological evaluation and SAR of sulfonamide 4-methoxychalcone derivatives with potential antileishmanial activity.
Andrighetti-Fröhner CR, de Oliveira KN, Gaspar-Silva D, Pacheco LK, Joussef AC, Steindel M, Simões CM, de Souza AM, Magalhaes UO, Afonso IF, Rodrigues CR, Nunes RJ, Castro HC. Andrighetti-Fröhner CR, et al. Eur J Med Chem. 2009 Feb;44(2):755-63. doi: 10.1016/j.ejmech.2008.04.016. Epub 2008 May 6. Eur J Med Chem. 2009. PMID: 18554753
26 results