Rodrigues CR - Search Results

1

Discovery of a new isomannide-based peptidomimetic synthetized by Ugi multicomponent reaction as human tissue kallikrein 1 inhibitor.

Barros TG, Santos JAN, de Souza BEG, Sodero ACR, de Souza AMT, da Silva DP, Rodrigues CR, Pinheiro S, Dias LRS, Abrahim-Vieira B, Puzer L, Muri EMF. Barros TG, et al. Among authors: rodrigues cr. Bioorg Med Chem Lett. 2017 Jan 15;27(2):314-318. doi: 10.1016/j.bmcl.2016.11.051. Epub 2016 Nov 18. Bioorg Med Chem Lett. 2017. PMID: 27914800

2

Design and synthesis of novel potent antinociceptive agents: methyl-imidazolyl N-acylhydrazone derivatives.

Figueiredo JM, Câmara CA, Amarante EG, Miranda AL, Santos FM, Rodrigues CR, Fraga CA, Barreiro EJ. Figueiredo JM, et al. Among authors: rodrigues cr. Bioorg Med Chem. 2000 Sep;8(9):2243-8. doi: 10.1016/s0968-0896(00)00152-8. Bioorg Med Chem. 2000. PMID: 11026537

3

Selective PGHS-2 inhibitors: a rational approach for treatment of the inflammation.

Rodrigues CR, Veloso MP, Verli H, Fraga CA, Miranda AL, Barreiro EJ. Rodrigues CR, et al. Curr Med Chem. 2002 Apr;9(8):849-67. doi: 10.2174/0929867024606786. Curr Med Chem. 2002. PMID: 11966448 Review.

4

Novel phthalimide derivatives, designed as leukotriene D(4) receptor antagonists.

Lima LM, de Brito FC, de Souza SD, Miranda AL, Rodrigues CR, Fraga CA, Barreiro EJ. Lima LM, et al. Among authors: rodrigues cr. Bioorg Med Chem Lett. 2002 Jun 3;12(11):1533-5. doi: 10.1016/s0960-894x(02)00203-2. Bioorg Med Chem Lett. 2002. PMID: 12031336

5

CoMFA and HQSAR of acylhydrazide cruzain inhibitors.

Rodrigues CR, Flaherty TM, Springer C, McKerrow JH, Cohen FE. Rodrigues CR, et al. Bioorg Med Chem Lett. 2002 Jun 3;12(11):1537-41. doi: 10.1016/s0960-894x(02)00189-0. Bioorg Med Chem Lett. 2002. PMID: 12031337

6

Design, synthesis, and pharmacological profile of novel fused pyrazolo[4,3-d]pyridine and pyrazolo[3,4-b][1,8]naphthyridine isosteres: a new class of potent and selective acetylcholinesterase inhibitors.

Barreiro EJ, Camara CA, Verli H, Brazil-Más L, Castro NG, Cintra WM, Aracava Y, Rodrigues CR, Fraga CA. Barreiro EJ, et al. Among authors: rodrigues cr. J Med Chem. 2003 Mar 27;46(7):1144-52. doi: 10.1021/jm020391n. J Med Chem. 2003. PMID: 12646025

7

Trypanocidal agents with low cytotoxicity to mammalian cell line: a comparison of the theoretical and biological features of lapachone derivatives.

Ferreira VF, Jorqueira A, Souza AM, da Silva MN, de Souza MC, Gouvêa RM, Rodrigues CR, Pinto AV, Castro HC, Santos DO, Araújo HP, Bourguignon SC. Ferreira VF, et al. Among authors: rodrigues cr. Bioorg Med Chem. 2006 Aug 15;14(16):5459-66. doi: 10.1016/j.bmc.2006.04.046. Epub 2006 May 24. Bioorg Med Chem. 2006. PMID: 16725327

8

Design, synthesis, SAR, and biological evaluation of new 4-(phenylamino)thieno[2,3-b]pyridine derivatives.

Bernardino AM, da Silva Pinheiro LC, Rodrigues CR, Loureiro NI, Castro HC, Lanfredi-Rangel A, Sabatini-Lopes J, Borges JC, Carvalho JM, Romeiro GA, Ferreira VF, Frugulhetti IC, Vannier-Santos MA. Bernardino AM, et al. Among authors: rodrigues cr. Bioorg Med Chem. 2006 Aug 15;14(16):5765-70. doi: 10.1016/j.bmc.2006.03.013. Epub 2006 Jun 14. Bioorg Med Chem. 2006. PMID: 16781157

9

Synthesis, tuberculosis inhibitory activity, and SAR study of N-substituted-phenyl-1,2,3-triazole derivatives.

Costa MS, Boechat N, Rangel EA, da Silva Fde C, de Souza AM, Rodrigues CR, Castro HC, Junior IN, Lourenço MC, Wardell SM, Ferreira VF. Costa MS, et al. Among authors: rodrigues cr. Bioorg Med Chem. 2006 Dec 15;14(24):8644-53. doi: 10.1016/j.bmc.2006.08.019. Epub 2006 Sep 1. Bioorg Med Chem. 2006. PMID: 16949290

10

Synthesis, in vitro evaluation, and SAR studies of a potential antichagasic 1H-pyrazolo[3,4-b]pyridine series.

Dias LR, Santos MB, Albuquerque Sd, Castro HC, de Souza AM, Freitas AC, DiVaio MA, Cabral LM, Rodrigues CR. Dias LR, et al. Among authors: rodrigues cr. Bioorg Med Chem. 2007 Jan 1;15(1):211-9. doi: 10.1016/j.bmc.2006.09.067. Epub 2006 Oct 1. Bioorg Med Chem. 2007. PMID: 17064907

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