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Pathological concentration of zinc dramatically accelerates abnormal aggregation of full-length human Tau and thereby significantly increases Tau toxicity in neuronal cells.
Hu JY, Zhang DL, Liu XL, Li XS, Cheng XQ, Chen J, Du HN, Liang Y. Hu JY, et al. Among authors: liang y. Biochim Biophys Acta Mol Basis Dis. 2017 Feb;1863(2):414-427. doi: 10.1016/j.bbadis.2016.11.022. Epub 2016 Nov 23. Biochim Biophys Acta Mol Basis Dis. 2017. PMID: 27890528 Free article.
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