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A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism.
Hefzi H, Ang KS, Hanscho M, Bordbar A, Ruckerbauer D, Lakshmanan M, Orellana CA, Baycin-Hizal D, Huang Y, Ley D, Martinez VS, Kyriakopoulos S, Jiménez NE, Zielinski DC, Quek LE, Wulff T, Arnsdorf J, Li S, Lee JS, Paglia G, Loira N, Spahn PN, Pedersen LE, Gutierrez JM, King ZA, Lund AM, Nagarajan H, Thomas A, Abdel-Haleem AM, Zanghellini J, Kildegaard HF, Voldborg BG, Gerdtzen ZP, Betenbaugh MJ, Palsson BO, Andersen MR, Nielsen LK, Borth N, Lee DY, Lewis NE. Hefzi H, et al. Among authors: ley d. Cell Syst. 2016 Nov 23;3(5):434-443.e8. doi: 10.1016/j.cels.2016.10.020. Cell Syst. 2016. PMID: 27883890 Free PMC article.
Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion.
Gutierrez JM, Feizi A, Li S, Kallehauge TB, Hefzi H, Grav LM, Ley D, Baycin Hizal D, Betenbaugh MJ, Voldborg B, Faustrup Kildegaard H, Min Lee G, Palsson BO, Nielsen J, Lewis NE. Gutierrez JM, et al. Among authors: ley d. Nat Commun. 2020 Jan 2;11(1):68. doi: 10.1038/s41467-019-13867-y. Nat Commun. 2020. PMID: 31896772 Free PMC article.
Multiplex secretome engineering enhances recombinant protein production and purity.
Kol S, Ley D, Wulff T, Decker M, Arnsdorf J, Schoffelen S, Hansen AH, Jensen TL, Gutierrez JM, Chiang AWT, Masson HO, Palsson BO, Voldborg BG, Pedersen LE, Kildegaard HF, Lee GM, Lewis NE. Kol S, et al. Among authors: ley d. Nat Commun. 2020 Apr 20;11(1):1908. doi: 10.1038/s41467-020-15866-w. Nat Commun. 2020. PMID: 32313013 Free PMC article.
Author Correction: Evaluation of recombinant human IGF-1/IGFBP-3 on intraventricular hemorrhage prevention and survival in the preterm rabbit pup model.
Ekström C, Ortenlöf N, Kristiansson A, Holmqvist B, Jungner Å, Vallius S, Wang X, Hellström A, Barton N, Carey G, Ley D, Gram M. Ekström C, et al. Among authors: ley d. Sci Rep. 2024 Apr 24;14(1):9423. doi: 10.1038/s41598-024-60175-7. Sci Rep. 2024. PMID: 38658641 Free PMC article. No abstract available.
341 results