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Anti-CGRP antibodies block CGRP-induced diarrhea in mice.
Kaiser EA, Rea BJ, Kuburas A, Kovacevich BR, Garcia-Martinez LF, Recober A, Russo AF. Kaiser EA, et al. Among authors: kovacevich br. Neuropeptides. 2017 Aug;64:95-99. doi: 10.1016/j.npep.2016.11.004. Epub 2016 Nov 14. Neuropeptides. 2017. PMID: 27865545 Free PMC article.
Pharmacologic Characterization of ALD403, a Potent Neutralizing Humanized Monoclonal Antibody Against the Calcitonin Gene-Related Peptide.
Garcia-Martinez LF, Raport CJ, Ojala EW, Dutzar B, Anderson K, Stewart E, Kovacevich B, Baker B, Billgren J, Scalley-Kim M, Karasek C, Allison D, Latham JA. Garcia-Martinez LF, et al. J Pharmacol Exp Ther. 2020 Jul;374(1):93-103. doi: 10.1124/jpet.119.264671. Epub 2020 May 4. J Pharmacol Exp Ther. 2020. PMID: 32366601
Osteocyte control of bone formation via sclerostin, a novel BMP antagonist.
Winkler DG, Sutherland MK, Geoghegan JC, Yu C, Hayes T, Skonier JE, Shpektor D, Jonas M, Kovacevich BR, Staehling-Hampton K, Appleby M, Brunkow ME, Latham JA. Winkler DG, et al. Among authors: kovacevich br. EMBO J. 2003 Dec 1;22(23):6267-76. doi: 10.1093/emboj/cdg599. EMBO J. 2003. PMID: 14633986 Free PMC article.
Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein.
Brunkow ME, Gardner JC, Van Ness J, Paeper BW, Kovacevich BR, Proll S, Skonier JE, Zhao L, Sabo PJ, Fu Y, Alisch RS, Gillett L, Colbert T, Tacconi P, Galas D, Hamersma H, Beighton P, Mulligan J. Brunkow ME, et al. Among authors: kovacevich br. Am J Hum Genet. 2001 Mar;68(3):577-89. doi: 10.1086/318811. Epub 2001 Feb 9. Am J Hum Genet. 2001. PMID: 11179006 Free PMC article.