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Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
Balzarini J, François KO, Van Laethem K, Hoorelbeke B, Renders M, Auwerx J, Liekens S, Oki T, Igarashi Y, Schols D. Balzarini J, et al. Among authors: liekens s. Antimicrob Agents Chemother. 2010 Apr;54(4):1425-35. doi: 10.1128/AAC.01347-09. Epub 2010 Jan 4. Antimicrob Agents Chemother. 2010. PMID: 20047920 Free PMC article.
Anti-HIV-1 activity of a tripodal receptor that recognizes mannose oligomers.
Rivero-Buceta E, Carrero P, Casanova E, Doyagüez EG, Madrona A, Quesada E, Peréz-Pérez MJ, Mateos R, Bravo L, Mathys L, Noppen S, Kiselev E, Marchand C, Pommier Y, Liekens S, Balzarini J, Camarasa MJ, San-Félix A. Rivero-Buceta E, et al. Among authors: liekens s. Eur J Med Chem. 2015 Dec 1;106:132-43. doi: 10.1016/j.ejmech.2015.10.027. Epub 2015 Oct 21. Eur J Med Chem. 2015. PMID: 26540494 Free PMC article.
Structure-activity relationship studies on a Trp dendrimer with dual activities against HIV and enterovirus A71. Modifications on the amino acid.
Martínez-Gualda B, Sun L, Rivero-Buceta E, Flores A, Quesada E, Balzarini J, Noppen S, Liekens S, Schols D, Neyts J, Leyssen P, Mirabelli C, Camarasa MJ, San-Félix A. Martínez-Gualda B, et al. Among authors: liekens s. Antiviral Res. 2017 Mar;139:32-40. doi: 10.1016/j.antiviral.2016.12.010. Epub 2016 Dec 23. Antiviral Res. 2017. PMID: 28017762 Free article.
Viruses as key regulators of angiogenesis.
Vrancken K, Vervaeke P, Balzarini J, Liekens S. Vrancken K, et al. Among authors: liekens s. Rev Med Virol. 2011 May;21(3):181-200. doi: 10.1002/rmv.688. Rev Med Virol. 2011. PMID: 21538666 Review.
142 results