Zain R - Search Results

1

Disruption of Higher Order DNA Structures in Friedreich's Ataxia (GAA)n Repeats by PNA or LNA Targeting.

Bergquist H, Rocha CS, Álvarez-Asencio R, Nguyen CH, Rutland MW, Smith CI, Good L, Nielsen PE, Zain R. Bergquist H, et al. Among authors: zain r. PLoS One. 2016 Nov 15;11(11):e0165788. doi: 10.1371/journal.pone.0165788. eCollection 2016. PLoS One. 2016. PMID: 27846236 Free PMC article.

2

Design of a triple-helix-specific cleaving reagent.

Zain R, Marchand C, Sun J, Nguyen CH, Bisagni E, Garestier T, Hélène C. Zain R, et al. Chem Biol. 1999 Nov;6(11):771-7. doi: 10.1016/s1074-5521(99)80124-0. Chem Biol. 1999. PMID: 10574778

3

Optimization of triple-helix-directed DNA cleavage by benzoquinoquinoxaline-ethylenediaminetetraacetic acid conjugates.

Zain R, Polverari D, Nguyen CH, Blouquit Y, Bisagni E, Garestier T, Grierson DS, Sun JS. Zain R, et al. Chembiochem. 2003 Sep 5;4(9):856-62. doi: 10.1002/cbic.200300621. Chembiochem. 2003. PMID: 12964160

4

Triple-helix directed cleavage of double-stranded DNA by benzoquinoquinoxaline-1,10-phenanthroline conjugates.

Zaid A, Sun JS, Nguyen CH, Bisagni E, Garestier T, Grierson DS, Zain R. Zaid A, et al. Among authors: zain r. Chembiochem. 2004 Nov 5;5(11):1550-7. doi: 10.1002/cbic.200400074. Chembiochem. 2004. PMID: 15515089

5

Benzoquinoquinoxaline derivatives stabilize and cleave H-DNA and repress transcription downstream of a triplex-forming sequence.

Amiri H, Nekhotiaeva N, Sun JS, Nguyen CH, Grierson DS, Good L, Zain R. Amiri H, et al. Among authors: zain r. J Mol Biol. 2005 Aug 26;351(4):776-83. doi: 10.1016/j.jmb.2005.03.044. Epub 2005 Apr 13. J Mol Biol. 2005. PMID: 16045927

6

Antisense PNA accumulates in Escherichia coli and mediates a long post-antibiotic effect.

Nikravesh A, Dryselius R, Faridani OR, Goh S, Sadeghizadeh M, Behmanesh M, Ganyu A, Klok EJ, Zain R, Good L. Nikravesh A, et al. Among authors: zain r. Mol Ther. 2007 Aug;15(8):1537-42. doi: 10.1038/sj.mt.6300209. Epub 2007 May 29. Mol Ther. 2007. PMID: 17534267 Free article.

7

Structure-specific recognition of Friedreich's ataxia (GAA)n repeats by benzoquinoquinoxaline derivatives.

Bergquist H, Nikravesh A, Fernández RD, Larsson V, Nguyen CH, Good L, Zain R. Bergquist H, et al. Among authors: zain r. Chembiochem. 2009 Nov 2;10(16):2629-37. doi: 10.1002/cbic.200900263. Chembiochem. 2009. PMID: 19746387

8

Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA.

Moreno PM, Geny S, Pabon YV, Bergquist H, Zaghloul EM, Rocha CS, Oprea II, Bestas B, Andaloussi SE, Jørgensen PT, Pedersen EB, Lundin KE, Zain R, Wengel J, Smith CI. Moreno PM, et al. Among authors: zain r. Nucleic Acids Res. 2013 Mar 1;41(5):3257-73. doi: 10.1093/nar/gkt007. Epub 2013 Jan 23. Nucleic Acids Res. 2013. PMID: 23345620 Free PMC article.

9

A distinct triplex DNA unwinding activity of ChlR1 helicase.

Guo M, Hundseth K, Ding H, Vidhyasagar V, Inoue A, Nguyen CH, Zain R, Lee JS, Wu Y. Guo M, et al. Among authors: zain r. J Biol Chem. 2015 Feb 20;290(8):5174-5189. doi: 10.1074/jbc.M114.634923. Epub 2015 Jan 5. J Biol Chem. 2015. PMID: 25561740 Free PMC article.

10

Next-generation bis-locked nucleic acids with stacking linker and 2'-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes.

Geny S, Moreno PM, Krzywkowski T, Gissberg O, Andersen NK, Isse AJ, El-Madani AM, Lou C, Pabon YV, Anderson BA, Zaghloul EM, Zain R, Hrdlicka PJ, Jørgensen PT, Nilsson M, Lundin KE, Pedersen EB, Wengel J, Smith CI. Geny S, et al. Among authors: zain r. Nucleic Acids Res. 2016 Mar 18;44(5):2007-19. doi: 10.1093/nar/gkw021. Epub 2016 Feb 8. Nucleic Acids Res. 2016. PMID: 26857548 Free PMC article.

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