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Carvacrol reduces irinotecan-induced intestinal mucositis through inhibition of inflammation and oxidative damage via TRPA1 receptor activation.
Alvarenga EM, Souza LK, Araújo TS, Nogueira KM, Sousa FB, Araújo AR, Martins CS, Pacífico DM, de C Brito GA, Souza EP, Sousa DP, Medeiros JV. Alvarenga EM, et al. Among authors: sousa fb, sousa dp. Chem Biol Interact. 2016 Dec 25;260:129-140. doi: 10.1016/j.cbi.2016.11.009. Epub 2016 Nov 9. Chem Biol Interact. 2016. PMID: 27838229
Anti-inflammatory effect of the monoterpene myrtenol is dependent on the direct modulation of neutrophil migration and oxidative stress.
Gomes BS, Neto BPS, Lopes EM, Cunha FVM, Araújo AR, Wanderley CWS, Wong DVT, Júnior RCPL, Ribeiro RA, Sousa DP, Venes R Medeiros J, Oliveira RCM, Oliveira FA. Gomes BS, et al. Among authors: sousa dp. Chem Biol Interact. 2017 Aug 1;273:73-81. doi: 10.1016/j.cbi.2017.05.019. Epub 2017 May 27. Chem Biol Interact. 2017. PMID: 28559105 Free article.
Carvacryl acetate, a novel semisynthetic monoterpene ester, binds to the TRPA1 receptor and is effective in attenuating irinotecan-induced intestinal mucositis in mice.
Alvarenga EM, Sousa NA, de Araújo S, Júnior JLP, Araújo AR, Iles B, Pacífico DM, Brito GAC, Souza EP, Sousa DP, Medeiros JVR. Alvarenga EM, et al. Among authors: sousa dp, sousa na. J Pharm Pharmacol. 2017 Dec;69(12):1773-1785. doi: 10.1111/jphp.12818. Epub 2017 Sep 21. J Pharm Pharmacol. 2017. PMID: 28940490
Efficacy of a phenol derivative, isopropyl vanillate, as an anti-inflammatory agent: A new small molecule inhibitor of COX and neutrophil migration.
Nogueira KM, de Souza LKM, de Oliveira AP, Pacheco G, Iles B, Alencar MS, Nicolau LAD, Silva RO, da Nóbrega FR, Sousa DP, de Souza MHLP, Medeiros JVR. Nogueira KM, et al. Among authors: sousa dp. Drug Dev Res. 2019 Aug;80(5):666-679. doi: 10.1002/ddr.21546. Epub 2019 May 21. Drug Dev Res. 2019. PMID: 31112325
α-Phellandrene attenuates tissular damage, oxidative stress, and TNF-α levels on acute model ifosfamide-induced hemorrhagic cystitis in mice.
Gonçalves RLG, Cunha FVM, Sousa-Neto BPS, Oliveira LSA, Lopes ME, Rezende DC, Sousa IJO, Nogueira KM, Souza LKM, Medeiros JVR, Wong DVT, Pereira VMP, Lima-Júnior RCP, Sousa DP, Oliveira CPC, Almeida FRC, Oliveira FA. Gonçalves RLG, et al. Among authors: sousa neto bps, sousa dp, sousa ijo. Naunyn Schmiedebergs Arch Pharmacol. 2020 Oct;393(10):1835-1848. doi: 10.1007/s00210-020-01869-3. Epub 2020 May 15. Naunyn Schmiedebergs Arch Pharmacol. 2020. PMID: 32415495
Correction to: α-Phellandrene attenuates tissular damage, oxidative stress, and TNF-α levels on acute model ifosfamide-induced hemorrhagic cystitis in mice.
Gonçalves RLG, Cunha FVM, Sousa-Neto BPS, Oliveira LSA, Lopes ME, Rezende DC, Sousa IJO, Nogueira KM, Souza LKM, Medeiros JVR, Wong DVT, Pereira VMP, Lima-Júnior RCP, Sousa DP, Oliveira CPC, Almeida FRC, de Assis Oliveira F. Gonçalves RLG, et al. Among authors: sousa neto bps, sousa dp, sousa ijo. Naunyn Schmiedebergs Arch Pharmacol. 2020 Dec;393(12):2553-2554. doi: 10.1007/s00210-020-01994-z. Naunyn Schmiedebergs Arch Pharmacol. 2020. PMID: 33064165
Cytotoxic and Antileishmanial Effects of the Monoterpene β-Ocimene.
Sousa JMS, Nunes TAL, Rodrigues RRL, Sousa JPA, Val MDCA, Coelho FADR, Santos ALSD, Maciel NB, Souza VMR, Machado YAA, Sousa PSA, Araújo AR, Rocha JA, Sousa DP, Silva MVD, Arcanjo DDR, Rodrigues KADF. Sousa JMS, et al. Among authors: sousa dp, sousa psa, sousa jpa. Pharmaceuticals (Basel). 2023 Jan 26;16(2):183. doi: 10.3390/ph16020183. Pharmaceuticals (Basel). 2023. PMID: 37259336 Free PMC article.
220 results