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Pharmacological Inhibition of Myocardin-related Transcription Factor Pathway Blocks Lung Metastases of RhoC-Overexpressing Melanoma.
Haak AJ, Appleton KM, Lisabeth EM, Misek SA, Ji Y, Wade SM, Bell JL, Rockwell CE, Airik M, Krook MA, Larsen SD, Verhaegen M, Lawlor ER, Neubig RR. Haak AJ, et al. Among authors: verhaegen m. Mol Cancer Ther. 2017 Jan;16(1):193-204. doi: 10.1158/1535-7163.MCT-16-0482. Epub 2016 Nov 11. Mol Cancer Ther. 2017. PMID: 27837031 Free PMC article.
A novel BH3 mimetic reveals a mitogen-activated protein kinase-dependent mechanism of melanoma cell death controlled by p53 and reactive oxygen species.
Verhaegen M, Bauer JA, Martín de la Vega C, Wang G, Wolter KG, Brenner JC, Nikolovska-Coleska Z, Bengtson A, Nair R, Elder JT, Van Brocklin M, Carey TE, Bradford CR, Wang S, Soengas MS. Verhaegen M, et al. Cancer Res. 2006 Dec 1;66(23):11348-59. doi: 10.1158/0008-5472.CAN-06-1748. Cancer Res. 2006. PMID: 17145881
Melanoma proliferation and chemoresistance controlled by the DEK oncogene.
Khodadoust MS, Verhaegen M, Kappes F, Riveiro-Falkenbach E, Cigudosa JC, Kim DS, Chinnaiyan AM, Markovitz DM, Soengas MS. Khodadoust MS, et al. Among authors: verhaegen m. Cancer Res. 2009 Aug 15;69(16):6405-13. doi: 10.1158/0008-5472.CAN-09-1063. Cancer Res. 2009. PMID: 19679545 Free PMC article.
Anti-oxidant treatment enhances anti-tumor cytotoxicity of (-)-gossypol.
Sikora MJ, Bauer JA, Verhaegen M, Belbin TJ, Prystowsky MB, Taylor JC, Brenner JC, Wang S, Soengas MS, Bradford CR, Carey TE. Sikora MJ, et al. Among authors: verhaegen m. Cancer Biol Ther. 2008 May;7(5):767-76. doi: 10.4161/cbt.7.5.5767. Epub 2008 May 20. Cancer Biol Ther. 2008. PMID: 18376141 Free PMC article.
148 results