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Page 1
Intradiscal delivery of celecoxib-loaded microspheres restores intervertebral disc integrity in a preclinical canine model.
Tellegen AR, Rudnik-Jansen I, Beukers M, Miranda-Bedate A, Bach FC, de Jong W, Woike N, Mihov G, Thies JC, Meij BP, Creemers LB, Tryfonidou MA. Tellegen AR, et al. Among authors: woike n. J Control Release. 2018 Sep 28;286:439-450. doi: 10.1016/j.jconrel.2018.08.019. Epub 2018 Aug 12. J Control Release. 2018. PMID: 30110616 Free article.
Prolonged inhibition of inflammation in osteoarthritis by triamcinolone acetonide released from a polyester amide microsphere platform.
Rudnik-Jansen I, Colen S, Berard J, Plomp S, Que I, van Rijen M, Woike N, Egas A, van Osch G, van Maarseveen E, Messier K, Chan A, Thies J, Creemers L. Rudnik-Jansen I, et al. Among authors: woike n. J Control Release. 2017 May 10;253:64-72. doi: 10.1016/j.jconrel.2017.03.014. Epub 2017 Mar 9. J Control Release. 2017. PMID: 28284832 Free article.
Controlled release of celecoxib inhibits inflammation, bone cysts and osteophyte formation in a preclinical model of osteoarthritis.
Tellegen AR, Rudnik-Jansen I, Pouran B, de Visser HM, Weinans HH, Thomas RE, Kik MJL, Grinwis GCM, Thies JC, Woike N, Mihov G, Emans PJ, Meij BP, Creemers LB, Tryfonidou MA. Tellegen AR, et al. Among authors: woike n. Drug Deliv. 2018 Nov;25(1):1438-1447. doi: 10.1080/10717544.2018.1482971. Drug Deliv. 2018. PMID: 29890922 Free PMC article.
Local controlled release of corticosteroids extends surgically induced joint instability by inhibiting tissue healing.
Rudnik-Jansen I, Tellegen AR, Pouran B, Schrijver K, Meij BP, Emans PJ, de Gendt E, Thomas RE, Kik MJL, de Visser HM, Weinans H, Egas A, van Maarseveen E, Woike N, Mihov G, Thies J, Tryfonidou MA, Creemers LB. Rudnik-Jansen I, et al. Among authors: woike n. Br J Pharmacol. 2019 Oct;176(20):4050-4064. doi: 10.1111/bph.14817. Epub 2019 Oct 8. Br J Pharmacol. 2019. PMID: 31378925 Free PMC article.