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Simultaneous blockade of interacting CK2 and EGFR pathways by tumor-targeting nanobioconjugates increases therapeutic efficacy against glioblastoma multiforme.
Chou ST, Patil R, Galstyan A, Gangalum PR, Cavenee WK, Furnari FB, Ljubimov VA, Chesnokova A, Kramerov AA, Ding H, Falahatian V, Mashouf L, Fox I, Black KL, Holler E, Ljubimov AV, Ljubimova JY. Chou ST, et al. Among authors: holler e. J Control Release. 2016 Dec 28;244(Pt A):14-23. doi: 10.1016/j.jconrel.2016.11.001. Epub 2016 Nov 5. J Control Release. 2016. PMID: 27825958 Free PMC article.
Polymalic acid nanobioconjugate for simultaneous immunostimulation and inhibition of tumor growth in HER2/neu-positive breast cancer.
Ding H, Helguera G, Rodríguez JA, Markman J, Luria-Pérez R, Gangalum P, Portilla-Arias J, Inoue S, Daniels-Wells TR, Black K, Holler E, Penichet ML, Ljubimova JY. Ding H, et al. Among authors: holler e. J Control Release. 2013 Nov 10;171(3):322-9. doi: 10.1016/j.jconrel.2013.06.001. Epub 2013 Jun 12. J Control Release. 2013. PMID: 23770212 Free PMC article.
Toxicity and efficacy evaluation of multiple targeted polymalic acid conjugates for triple-negative breast cancer treatment.
Ljubimova JY, Portilla-Arias J, Patil R, Ding H, Inoue S, Markman JL, Rekechenetskiy A, Konda B, Gangalum PR, Chesnokova A, Ljubimov AV, Black KL, Holler E. Ljubimova JY, et al. Among authors: holler e. J Drug Target. 2013 Dec;21(10):956-967. doi: 10.3109/1061186X.2013.837470. Epub 2013 Sep 16. J Drug Target. 2013. PMID: 24032759 Free PMC article.
MRI virtual biopsy and treatment of brain metastatic tumors with targeted nanobioconjugates: nanoclinic in the brain.
Patil R, Ljubimov AV, Gangalum PR, Ding H, Portilla-Arias J, Wagner S, Inoue S, Konda B, Rekechenetskiy A, Chesnokova A, Markman JL, Ljubimov VA, Li D, Prasad RS, Black KL, Holler E, Ljubimova JY. Patil R, et al. Among authors: holler e. ACS Nano. 2015 May 26;9(5):5594-608. doi: 10.1021/acsnano.5b01872. Epub 2015 May 6. ACS Nano. 2015. PMID: 25906400 Free PMC article.
Covalent nano delivery systems for selective imaging and treatment of brain tumors.
Ljubimova JY, Sun T, Mashouf L, Ljubimov AV, Israel LL, Ljubimov VA, Falahatian V, Holler E. Ljubimova JY, et al. Among authors: holler e. Adv Drug Deliv Rev. 2017 Apr;113:177-200. doi: 10.1016/j.addr.2017.06.002. Epub 2017 Jun 10. Adv Drug Deliv Rev. 2017. PMID: 28606739 Free PMC article. Review.
Blockade of a Laminin-411-Notch Axis with CRISPR/Cas9 or a Nanobioconjugate Inhibits Glioblastoma Growth through Tumor-Microenvironment Cross-talk.
Sun T, Patil R, Galstyan A, Klymyshyn D, Ding H, Chesnokova A, Cavenee WK, Furnari FB, Ljubimov VA, Shatalova ES, Wagner S, Li D, Mamelak AN, Bannykh SI, Patil CG, Rudnick JD, Hu J, Grodzinski ZB, Rekechenetskiy A, Falahatian V, Lyubimov AV, Chen YL, Leoh LS, Daniels-Wells TR, Penichet ML, Holler E, Ljubimov AV, Black KL, Ljubimova JY. Sun T, et al. Among authors: holler e. Cancer Res. 2019 Mar 15;79(6):1239-1251. doi: 10.1158/0008-5472.CAN-18-2725. Epub 2019 Jan 18. Cancer Res. 2019. PMID: 30659021 Free PMC article.
Blood-brain barrier permeable nano immunoconjugates induce local immune responses for glioma therapy.
Galstyan A, Markman JL, Shatalova ES, Chiechi A, Korman AJ, Patil R, Klymyshyn D, Tourtellotte WG, Israel LL, Braubach O, Ljubimov VA, Mashouf LA, Ramesh A, Grodzinski ZB, Penichet ML, Black KL, Holler E, Sun T, Ding H, Ljubimov AV, Ljubimova JY. Galstyan A, et al. Among authors: holler e. Nat Commun. 2019 Aug 28;10(1):3850. doi: 10.1038/s41467-019-11719-3. Nat Commun. 2019. PMID: 31462642 Free PMC article.
608 results