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Regulation of autoantibody activity by the IL-23-TH17 axis determines the onset of autoimmune disease.
Pfeifle R, Rothe T, Ipseiz N, Scherer HU, Culemann S, Harre U, Ackermann JA, Seefried M, Kleyer A, Uderhardt S, Haugg B, Hueber AJ, Daum P, Heidkamp GF, Ge C, Böhm S, Lux A, Schuh W, Magorivska I, Nandakumar KS, Lönnblom E, Becker C, Dudziak D, Wuhrer M, Rombouts Y, Koeleman CA, Toes R, Winkler TH, Holmdahl R, Herrmann M, Blüml S, Nimmerjahn F, Schett G, Krönke G. Pfeifle R, et al. Among authors: daum p. Nat Immunol. 2017 Jan;18(1):104-113. doi: 10.1038/ni.3579. Epub 2016 Nov 7. Nat Immunol. 2017. PMID: 27820809 Free PMC article.
miR-148a promotes plasma cell differentiation and targets the germinal center transcription factors Mitf and Bach2.
Porstner M, Winkelmann R, Daum P, Schmid J, Pracht K, Côrte-Real J, Schreiber S, Haftmann C, Brandl A, Mashreghi MF, Gelse K, Hauke M, Wirries I, Zwick M, Roth E, Radbruch A, Wittmann J, Jäck HM. Porstner M, et al. Among authors: daum p. Eur J Immunol. 2015 Apr;45(4):1206-15. doi: 10.1002/eji.201444637. Epub 2015 Mar 12. Eur J Immunol. 2015. PMID: 25678371 Free article.
IRF4 deficiency vulnerates B-cell progeny for leukemogenesis via somatically acquired Jak3 mutations conferring IL-7 hypersensitivity.
Das Gupta D, Paul C, Samel N, Bieringer M, Staudenraus D, Marini F, Raifer H, Menke L, Hansal L, Camara B, Roth E, Daum P, Wanzel M, Mernberger M, Nist A, Bauer UM, Helmprobst F, Buchholz M, Roth K, Bastian L, Hartmann AM, Baldus C, Ikuta K, Neubauer A, Burchert A, Jäck HM, Klein M, Bopp T, Stiewe T, Pagenstecher A, Lohoff M. Das Gupta D, et al. Among authors: daum p. Cell Death Differ. 2022 Nov;29(11):2163-2176. doi: 10.1038/s41418-022-01005-z. Epub 2022 Apr 22. Cell Death Differ. 2022. PMID: 35459909 Free PMC article.
44 results