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Inhibition of RAS function through targeting an allosteric regulatory site.
Nat Chem Biol. 2017 Jan;13(1):62-68. doi: 10.1038/nchembio.2231. Epub 2016 Nov 7.
Nat Chem Biol. 2017.
PMID: 27820802
Free PMC article.
Optical control of fast and processive engineered myosins in vitro and in living cells.
Ruijgrok PV, Ghosh RP, Zemsky S, Nakamura M, Gong R, Ning L, Chen R, Vachharajani VT, Chu AE, Anand N, Eguchi RR, Huang PS, Lin MZ, Alushin GM, Liphardt JT, Bryant Z.
Ruijgrok PV, et al. Among authors: eguchi rr.
Nat Chem Biol. 2021 May;17(5):540-548. doi: 10.1038/s41589-021-00740-7. Epub 2021 Feb 18.
Nat Chem Biol. 2021.
PMID: 33603247
Free PMC article.
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Protein sequence design with a learned potential.
Anand N, Eguchi R, Mathews II, Perez CP, Derry A, Altman RB, Huang PS.
Anand N, et al.
Nat Commun. 2022 Feb 8;13(1):746. doi: 10.1038/s41467-022-28313-9.
Nat Commun. 2022.
PMID: 35136054
Free PMC article.
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Multi-scale structural analysis of proteins by deep semantic segmentation.
Eguchi RR, Huang PS.
Eguchi RR, et al.
Bioinformatics. 2020 Mar 1;36(6):1740-1749. doi: 10.1093/bioinformatics/btz650.
Bioinformatics. 2020.
PMID: 31424530
Free PMC article.
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Ig-VAE: Generative modeling of protein structure by direct 3D coordinate generation.
Eguchi RR, Choe CA, Huang PS.
Eguchi RR, et al.
PLoS Comput Biol. 2022 Jun 27;18(6):e1010271. doi: 10.1371/journal.pcbi.1010271. eCollection 2022 Jun.
PLoS Comput Biol. 2022.
PMID: 35759518
Free PMC article.
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De Novo Design of a Highly Stable Ovoid TIM Barrel: Unlocking Pocket Shape towards Functional Design.
Chu AE, Fernandez D, Liu J, Eguchi RR, Huang PS.
Chu AE, et al. Among authors: eguchi rr.
Biodes Res. 2022 Oct 10;2022:9842315. doi: 10.34133/2022/9842315. eCollection 2022.
Biodes Res. 2022.
PMID: 37850141
Free PMC article.
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TRPC6 channel translocation into phagosomal membrane augments phagosomal function.
Riazanski V, Gabdoulkhakova AG, Boynton LS, Eguchi RR, Deriy LV, Hogarth DK, Loaëc N, Oumata N, Galons H, Brown ME, Shevchenko P, Gallan AJ, Yoo SG, Naren AP, Villereal ML, Beacham DW, Bindokas VP, Birnbaumer L, Meijer L, Nelson DJ.
Riazanski V, et al. Among authors: eguchi rr.
Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6486-95. doi: 10.1073/pnas.1518966112. Epub 2015 Nov 10.
Proc Natl Acad Sci U S A. 2015.
PMID: 26604306
Free PMC article.
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