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The fully synthetic MAG-Tn3 therapeutic vaccine containing the tetanus toxoid-derived TT830-844 universal epitope provides anti-tumor immunity.
Laubreton D, Bay S, Sedlik C, Artaud C, Ganneau C, Dériaud E, Viel S, Puaux AL, Amigorena S, Gérard C, Lo-Man R, Leclerc C. Laubreton D, et al. Among authors: deriaud e. Cancer Immunol Immunother. 2016 Mar;65(3):315-25. doi: 10.1007/s00262-016-1802-0. Epub 2016 Feb 4. Cancer Immunol Immunother. 2016. PMID: 26847142 Free PMC article.
Design, Synthesis, and Immunological Evaluation of a Multicomponent Construct Based on a Glycotripeptoid Core Comprising B and T Cell Epitopes and a Toll-like Receptor 7 Agonist That Elicits Potent Immune Responses.
Szekely T, Roy O, Dériaud E, Job A, Lo-Man R, Leclerc C, Taillefumier C. Szekely T, et al. Among authors: deriaud e. J Med Chem. 2018 Nov 8;61(21):9568-9582. doi: 10.1021/acs.jmedchem.8b00960. Epub 2018 Oct 23. J Med Chem. 2018. PMID: 30351939
51 results