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Effects of astaxanthin on gut microbiota of polo ponies during deconditioning and reconditioning periods.
Kawaida MY, Maas KR, Moore TE, Reiter AS, Tillquist NM, Reed SA. Kawaida MY, et al. Physiol Rep. 2024 Jun;12(11):e16051. doi: 10.14814/phy2.16051. Physiol Rep. 2024. PMID: 38811348
To determine the effects of astaxanthin (ASTX) supplementation on the equine gut microbiota during a deconditioning-reconditioning cycle, 12 polo ponies were assigned to a control (CON; n = 6) or supplemented (ASTX; 75 mg ASTX daily orally; n = 6) group. ...
To determine the effects of astaxanthin (ASTX) supplementation on the equine gut microbiota during a deconditioning-reconditioning cycle, 12 …
Opinions regarding equine veterinarian attire and attributes: results of a horse owner survey.
O'Neil EK, Fogle CA, Sheats MK, Love K. O'Neil EK, et al. J Am Vet Med Assoc. 2024 May 29:1-9. doi: 10.2460/javma.24.02.0083. Online ahead of print. J Am Vet Med Assoc. 2024. PMID: 38810658
The highest-ranked traits in an equine veterinarian were knowledge/competency (mean SD, 1.46 0.98), followed by trustworthiness (2.34 1.08) and compassion (3.50 1.20), with coveralls and scrubs being the preferred attire clients associated with these attributes (with the exceptio …
The highest-ranked traits in an equine veterinarian were knowledge/competency (mean SD, 1.46 0.98), followed by trustworthiness (2.34 1.08) …
A new framework for novel analogues of pazopanib as potent and selective human carbonic anhydrase inhibitors: Design, repurposing rational, synthesis, crystallographic, in vivo and in vitro biological assessments.
Hefny SM, El-Moselhy TF, El-Din N, Ammara A, Angeli A, Ferraroni M, El-Dessouki AM, Shaldam MA, Yahya G, Al-Karmalawy AA, Supuran CT, Tawfik HO. Hefny SM, et al. Eur J Med Chem. 2024 May 24;274:116527. doi: 10.1016/j.ejmech.2024.116527. Online ahead of print. Eur J Med Chem. 2024. PMID: 38810335
PLK1 inhibition leads to mitotic arrest and triggers apoptosis in cholangiocarcinoma cells.
Moolmuang B, Chaisaingmongkol J, Singhirunnusorn P, Ruchirawat M. Moolmuang B, et al. Oncol Lett. 2024 May 14;28(1):316. doi: 10.3892/ol.2024.14449. eCollection 2024 Jul. Oncol Lett. 2024. PMID: 38807667 Free PMC article.
Cholangiocarcinoma (CCA) is a lethal cancer originating from the epithelial cells within the bile duct and ranks as the second most prevalent form of liver cancer in Thailand. Polo-like kinase 1 (PLK1), a protein serine/threonine kinase, regulates a number of steps in cell …
Cholangiocarcinoma (CCA) is a lethal cancer originating from the epithelial cells within the bile duct and ranks as the second most prevalen …
Estimation of the optimal radiotherapy utilization rate for childhood neuroblastoma.
Fukushima A, Hande V, Wakeham K, Barton MB, Zaghloul MS, Moreira DC, Bhakta N, Pritchard-Jones K, Sullivan M, Mazhar Qureshi B, Njiraini PN, Polo A. Fukushima A, et al. Radiother Oncol. 2024 May 26:110343. doi: 10.1016/j.radonc.2024.110343. Online ahead of print. Radiother Oncol. 2024. PMID: 38806114
Emerging role of immunogenic cell death in cancer immunotherapy.
Arimoto KI, Miyauchi S, Liu M, Zhang DE. Arimoto KI, et al. Front Immunol. 2024 May 10;15:1390263. doi: 10.3389/fimmu.2024.1390263. eCollection 2024. Front Immunol. 2024. PMID: 38799433 Free PMC article. Review.
Our recent findings are also highlighted, revealing a mode of ICD induction facilitated by atypical interferon (IFN)-stimulated genes (ISGs), including polo-like kinase 2 (PLK2), during hyperactive type I IFN signaling. ...
Our recent findings are also highlighted, revealing a mode of ICD induction facilitated by atypical interferon (IFN)-stimulated genes (ISGs) …
Rational design of HER2-targeted combination therapies to reverse drug resistance in fibroblast-protected HER2+ breast cancer cells.
Poskus MD, McDonald J, Laird M, Li R, Norcoss K, Zervantonakis IK. Poskus MD, et al. bioRxiv [Preprint]. 2024 May 19:2024.05.18.594826. doi: 10.1101/2024.05.18.594826. bioRxiv. 2024. PMID: 38798591 Free PMC article. Preprint.
RESULTS: Compared to monoculture, fibroblast-conditioned medium increased the expression of plasminogen activator inhibitor-1 (PAI1) and cell cycle regulator polo like kinase 1 (PLK1) in lapatinib-treated breast cancer cells. ...
RESULTS: Compared to monoculture, fibroblast-conditioned medium increased the expression of plasminogen activator inhibitor-1 (PAI1) and cel …
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