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Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity.
Dendrou CA, Cortes A, Shipman L, Evans HG, Attfield KE, Jostins L, Barber T, Kaur G, Kuttikkatte SB, Leach OA, Desel C, Faergeman SL, Cheeseman J, Neville MJ, Sawcer S, Compston A, Johnson AR, Everett C, Bell JI, Karpe F, Ultsch M, Eigenbrot C, McVean G, Fugger L. Dendrou CA, et al. Among authors: leach oa. Sci Transl Med. 2016 Nov 2;8(363):363ra149. doi: 10.1126/scitranslmed.aag1974. Sci Transl Med. 2016. PMID: 27807284 Free PMC article.
TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis.
Gregory AP, Dendrou CA, Attfield KE, Haghikia A, Xifara DK, Butter F, Poschmann G, Kaur G, Lambert L, Leach OA, Prömel S, Punwani D, Felce JH, Davis SJ, Gold R, Nielsen FC, Siegel RM, Mann M, Bell JI, McVean G, Fugger L. Gregory AP, et al. Among authors: leach oa. Nature. 2012 Aug 23;488(7412):508-511. doi: 10.1038/nature11307. Nature. 2012. PMID: 22801493 Free PMC article.
Acute Inflammatory Diseases of the Central Nervous System After SARS-CoV-2 Vaccination.
Francis AG, Elhadd K, Camera V, Ferreira Dos Santos M, Rocchi C, Adib-Samii P, Athwal B, Attfield K, Barritt A, Craner M, Fisniku L, Iversen AKN, Leach O, Matthews L, Redmond I, O'Riordan J, Scalfari A, Tanasescu R, Wren D, Huda S, Leite MI, Fugger L, Palace J. Francis AG, et al. Neurol Neuroimmunol Neuroinflamm. 2022 Nov 21;10(1):e200063. doi: 10.1212/NXI.0000000000200063. Print 2023 Jan. Neurol Neuroimmunol Neuroinflamm. 2022. PMID: 36411077 Free PMC article.
A young woman with rigors and abdominal pain.
Leach OA, Gilbert EJ, Evans A, van Boxel GI. Leach OA, et al. BMJ. 2011 Mar 9;342:d689. doi: 10.1136/bmj.d689. BMJ. 2011. PMID: 21389069 No abstract available.