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Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma.
Hideshima T, Qi J, Paranal RM, Tang W, Greenberg E, West N, Colling ME, Estiu G, Mazitschek R, Perry JA, Ohguchi H, Cottini F, Mimura N, Görgün G, Tai YT, Richardson PG, Carrasco RD, Wiest O, Schreiber SL, Anderson KC, Bradner JE. Hideshima T, et al. Among authors: bradner je. Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):13162-13167. doi: 10.1073/pnas.1608067113. Epub 2016 Oct 31. Proc Natl Acad Sci U S A. 2016. PMID: 27799547 Free PMC article.
Intracellular protein degradation and its therapeutic implications.
Hideshima T, Bradner JE, Chauhan D, Anderson KC. Hideshima T, et al. Among authors: bradner je. Clin Cancer Res. 2005 Dec 15;11(24 Pt 1):8530-3. doi: 10.1158/1078-0432.CCR-05-2305. Clin Cancer Res. 2005. PMID: 16361533 Review. No abstract available.
A robust small-molecule microarray platform for screening cell lysates.
Bradner JE, McPherson OM, Mazitschek R, Barnes-Seeman D, Shen JP, Dhaliwal J, Stevenson KE, Duffner JL, Park SB, Neuberg DS, Nghiem P, Schreiber SL, Koehler AN. Bradner JE, et al. Chem Biol. 2006 May;13(5):493-504. doi: 10.1016/j.chembiol.2006.03.004. Chem Biol. 2006. PMID: 16720270
Lymphocyte chemotaxis is regulated by histone deacetylase 6, independently of its deacetylase activity.
Cabrero JR, Serrador JM, Barreiro O, Mittelbrunn M, Naranjo-Suárez S, Martín-Cófreces N, Vicente-Manzanares M, Mazitschek R, Bradner JE, Avila J, Valenzuela-Fernández A, Sánchez-Madrid F. Cabrero JR, et al. Among authors: bradner je. Mol Biol Cell. 2006 Aug;17(8):3435-45. doi: 10.1091/mbc.e06-01-0008. Epub 2006 May 31. Mol Biol Cell. 2006. PMID: 16738306 Free PMC article.
260 results