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Bis-picolinamide Ruthenium(III) Dihalide Complexes: Dichloride-to-Diiodide Exchange Generates Single trans Isomers with High Potency and Cancer Cell Selectivity.
Basri AM, Lord RM, Allison SJ, Rodríguez-Bárzano A, Lucas SJ, Janeway FD, Shepherd HJ, Pask CM, Phillips RM, McGowan PC. Basri AM, et al. Among authors: phillips rm. Chemistry. 2017 May 5;23(26):6341-6356. doi: 10.1002/chem.201605960. Epub 2017 Apr 7. Chemistry. 2017. PMID: 28225184 Free article.
Preclinical anti-cancer activity and multiple mechanisms of action of a cationic silver complex bearing N-heterocyclic carbene ligands.
Allison SJ, Sadiq M, Baronou E, Cooper PA, Dunnill C, Georgopoulos NT, Latif A, Shepherd S, Shnyder SD, Stratford IJ, Wheelhouse RT, Willans CE, Phillips RM. Allison SJ, et al. Among authors: phillips rm. Cancer Lett. 2017 Sep 10;403:98-107. doi: 10.1016/j.canlet.2017.04.041. Epub 2017 Jun 15. Cancer Lett. 2017. PMID: 28624622 Free article.
Anticancer metallohelices: nanomolar potency and high selectivity.
Kaner RA, Allison SJ, Faulkner AD, Phillips RM, Roper DI, Shepherd SL, Simpson DH, Waterfield NR, Scott P. Kaner RA, et al. Among authors: phillips rm. Chem Sci. 2016 Feb 1;7(2):951-958. doi: 10.1039/c5sc03677a. Epub 2015 Oct 26. Chem Sci. 2016. PMID: 28808525 Free PMC article.
Ruthenium-Containing Linear Helicates and Mesocates with Tuneable p53-Selective Cytotoxicity in Colorectal Cancer Cells.
Allison SJ, Cooke D, Davidson FS, Elliott PIP, Faulkner RA, Griffiths HBS, Harper OJ, Hussain O, Owen-Lynch PJ, Phillips RM, Rice CR, Shepherd SL, Wheelhouse RT. Allison SJ, et al. Among authors: phillips rm. Angew Chem Int Ed Engl. 2018 Jul 26;57(31):9799-9804. doi: 10.1002/anie.201805510. Epub 2018 Jul 3. Angew Chem Int Ed Engl. 2018. PMID: 29863754
Glycoconjugated Metallohelices have Improved Nuclear Delivery and Suppress Tumour Growth In Vivo.
Song H, Allison SJ, Brabec V, Bridgewater HE, Kasparkova J, Kostrhunova H, Novohradsky V, Phillips RM, Pracharova J, Rogers NJ, Shepherd SL, Scott P. Song H, et al. Among authors: phillips rm. Angew Chem Int Ed Engl. 2020 Aug 17;59(34):14677-14685. doi: 10.1002/anie.202006814. Epub 2020 Jul 7. Angew Chem Int Ed Engl. 2020. PMID: 32489012 Free PMC article.
214 results