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Page 1
CD70 limits atherosclerosis and promotes macrophage function.
Winkels H, Meiler S, Smeets E, Lievens D, Engel D, Spitz C, Bürger C, Rinne P, Beckers L, Dandl A, Reim S, Ahmadsei M, Van den Bossche J, Holdt LM, Megens RT, Schmitt M, de Winther M, Biessen EA, Borst J, Faussner A, Weber C, Lutgens E, Gerdes N. Winkels H, et al. Among authors: de winther m. Thromb Haemost. 2017 Jan 5;117(1):164-175. doi: 10.1160/TH16-04-0318. Epub 2016 Oct 27. Thromb Haemost. 2017. PMID: 27786334
Liposomal prednisolone promotes macrophage lipotoxicity in experimental atherosclerosis.
van der Valk FM, Schulte DM, Meiler S, Tang J, Zheng KH, Van den Bossche J, Seijkens T, Laudes M, de Winther M, Lutgens E, Alaarg A, Metselaar JM, Dallinga-Thie GM, Mulder WJ, Stroes ES, Hamers AA. van der Valk FM, et al. Among authors: de winther m. Nanomedicine. 2016 Aug;12(6):1463-70. doi: 10.1016/j.nano.2016.02.022. Epub 2016 Mar 23. Nanomedicine. 2016. PMID: 27015770
Myeloid CD40 deficiency reduces atherosclerosis by impairing macrophages' transition into a pro-inflammatory state.
Bosmans LA, van Tiel CM, Aarts SABM, Willemsen L, Baardman J, van Os BW, Toom MD, Beckers L, Ahern DJ, Levels JHM, Jongejan A, Moerland PD, Verberk SGS, den Bossche JV, de Winther MMPJ, Weber C, Atzler D, Monaco C, Gerdes N, Shami A, Lutgens E. Bosmans LA, et al. Among authors: de winther mmpj. Cardiovasc Res. 2023 May 22;119(5):1146-1160. doi: 10.1093/cvr/cvac084. Cardiovasc Res. 2023. PMID: 35587037 Free PMC article.
Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance.
Chatzigeorgiou A, Seijkens T, Zarzycka B, Engel D, Poggi M, van den Berg S, van den Berg S, Soehnlein O, Winkels H, Beckers L, Lievens D, Driessen A, Kusters P, Biessen E, Garcia-Martin R, Klotzsche-von Ameln A, Gijbels M, Noelle R, Boon L, Hackeng T, Schulte KM, Xu A, Vriend G, Nabuurs S, Chung KJ, Willems van Dijk K, Rensen PC, Gerdes N, de Winther M, Block NL, Schally AV, Weber C, Bornstein SR, Nicolaes G, Chavakis T, Lutgens E. Chatzigeorgiou A, et al. Among authors: de winther m. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2686-91. doi: 10.1073/pnas.1400419111. Epub 2014 Feb 3. Proc Natl Acad Sci U S A. 2014. PMID: 24492375 Free PMC article.
Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism.
Cribbs AP, Terlecki-Zaniewicz S, Philpott M, Baardman J, Ahern D, Lindow M, Obad S, Oerum H, Sampey B, Mander PK, Penn H, Wordsworth P, Bowness P, de Winther M, Prinjha RK, Feldmann M, Oppermann U. Cribbs AP, et al. Among authors: de winther m. Proc Natl Acad Sci U S A. 2020 Mar 17;117(11):6056-6066. doi: 10.1073/pnas.1919893117. Epub 2020 Mar 2. Proc Natl Acad Sci U S A. 2020. PMID: 32123118 Free PMC article.
Sexual dimorphism in atherosclerotic plaques of aged Ldlr-/- mice.
Smit V, de Mol J, Kleijn MNAB, Depuydt MAC, de Winther MPJ, Bot I, Kuiper J, Foks AC. Smit V, et al. Among authors: de winther mpj. Immun Ageing. 2024 May 2;21(1):27. doi: 10.1186/s12979-024-00434-3. Immun Ageing. 2024. PMID: 38698438 Free PMC article.
Atherosclerotic Plaque Epigenetic Age Acceleration Predicts a Poor Prognosis and Is Associated With Endothelial-to-Mesenchymal Transition in Humans.
Diez Benavente E, Hartman RJG, Sakkers TR, Wesseling M, Sloots Y, Slenders L, Boltjes A, Mol BM, de Borst GJ, de Kleijn DPV, Prange KHM, de Winther MPJ, Kuiper J, Civelek M, van der Laan SW, Horvath S, Onland-Moret NC, Mokry M, Pasterkamp G, den Ruijter HM. Diez Benavente E, et al. Among authors: de winther mpj. Arterioscler Thromb Vasc Biol. 2024 Jun;44(6):1419-1431. doi: 10.1161/ATVBAHA.123.320692. Epub 2024 Apr 18. Arterioscler Thromb Vasc Biol. 2024. PMID: 38634280 Free article.
T cell specific deletion of Casitas B lineage lymphoma-b reduces atherosclerosis, but increases plaque T cell infiltration and systemic T cell activation.
Vos WG, van Os BW, den Toom M, Beckers L, van Roomen CPAA, van Tiel CM, Mohapatra BC, Band H, Nitz K, Weber C, Atzler D, de Winther MPJ, Bosmans LA, Lutgens E, Seijkens TTP. Vos WG, et al. Among authors: de winther mpj. Front Immunol. 2024 Mar 4;15:1297893. doi: 10.3389/fimmu.2024.1297893. eCollection 2024. Front Immunol. 2024. PMID: 38504977 Free PMC article.
205 results