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Page 1
Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy.
Mangala LS, Wang H, Jiang D, Wu SY, Somasunderam A, Volk DE, Lokesh GLR, Li X, Pradeep S, Yang X, Haemmerle M, Rodriguez-Aguayo C, Nagaraja AS, Rupaimoole R, Bayraktar E, Bayraktar R, Li L, Tanaka T, Hu W, Ivan C, Gharpure KM, McGuire MH, Thiviyanathan V, Zhang X, Maiti SN, Bulayeva N, Choi HJ, Dorniak PL, Cooper LJ, Rosenblatt KP, Lopez-Berestein G, Gorenstein DG, Sood AK. Mangala LS, et al. Among authors: gharpure km. JCI Insight. 2016 Oct 20;1(17):e87754. doi: 10.1172/jci.insight.87754. JCI Insight. 2016. PMID: 27777972 Free PMC article.
Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression.
Rupaimoole R, Ivan C, Yang D, Gharpure KM, Wu SY, Pecot CV, Previs RA, Nagaraja AS, Armaiz-Pena GN, McGuire M, Pradeep S, Mangala LS, Rodriguez-Aguayo C, Huang L, Bar-Eli M, Zhang W, Lopez-Berestein G, Calin GA, Sood AK. Rupaimoole R, et al. Among authors: gharpure km. Oncogene. 2016 Aug 18;35(33):4312-20. doi: 10.1038/onc.2015.492. Epub 2016 Jan 4. Oncogene. 2016. PMID: 26725326 Free PMC article.
Antiangiogenic and tumour inhibitory effects of downregulating tumour endothelial FABP4.
Harjes U, Bridges E, Gharpure KM, Roxanis I, Sheldon H, Miranda F, Mangala LS, Pradeep S, Lopez-Berestein G, Ahmed A, Fielding B, Sood AK, Harris AL. Harjes U, et al. Among authors: gharpure km. Oncogene. 2017 Feb 16;36(7):912-921. doi: 10.1038/onc.2016.256. Epub 2016 Aug 29. Oncogene. 2017. PMID: 27568980 Free PMC article.
Clodronate inhibits tumor angiogenesis in mouse models of ovarian cancer.
Reusser NM, Dalton HJ, Pradeep S, Gonzalez-Villasana V, Jennings NB, Vasquez HG, Wen Y, Rupaimoole R, Nagaraja AS, Gharpure K, Miyake T, Huang J, Hu W, Lopez-Berestein G, Sood AK. Reusser NM, et al. Cancer Biol Ther. 2014 Aug;15(8):1061-7. doi: 10.4161/cbt.29184. Epub 2014 May 19. Cancer Biol Ther. 2014. PMID: 24841852 Free PMC article.
ATP11B mediates platinum resistance in ovarian cancer.
Moreno-Smith M, Halder JB, Meltzer PS, Gonda TA, Mangala LS, Rupaimoole R, Lu C, Nagaraja AS, Gharpure KM, Kang Y, Rodriguez-Aguayo C, Vivas-Mejia PE, Zand B, Schmandt R, Wang H, Langley RR, Jennings NB, Ivan C, Coffin JE, Armaiz GN, Bottsford-Miller J, Kim SB, Halleck MS, Hendrix MJ, Bornman W, Bar-Eli M, Lee JS, Siddik ZH, Lopez-Berestein G, Sood AK. Moreno-Smith M, et al. Among authors: gharpure km. J Clin Invest. 2013 May;123(5):2119-30. doi: 10.1172/JCI65425. Epub 2013 Apr 15. J Clin Invest. 2013. PMID: 23585472 Free PMC article.
Metronomic docetaxel in PRINT nanoparticles and EZH2 silencing have synergistic antitumor effect in ovarian cancer.
Gharpure KM, Chu KS, Bowerman CJ, Miyake T, Pradeep S, Mangala SL, Han HD, Rupaimoole R, Armaiz-Pena GN, Rahhal TB, Wu SY, Luft JC, Napier ME, Lopez-Berestein G, DeSimone JM, Sood AK. Gharpure KM, et al. Mol Cancer Ther. 2014 Jul;13(7):1750-7. doi: 10.1158/1535-7163.MCT-13-0930. Epub 2014 Apr 22. Mol Cancer Ther. 2014. PMID: 24755199 Free PMC article.
Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression.
Rupaimoole R, Wu SY, Pradeep S, Ivan C, Pecot CV, Gharpure KM, Nagaraja AS, Armaiz-Pena GN, McGuire M, Zand B, Dalton HJ, Filant J, Miller JB, Lu C, Sadaoui NC, Mangala LS, Taylor M, van den Beucken T, Koch E, Rodriguez-Aguayo C, Huang L, Bar-Eli M, Wouters BG, Radovich M, Ivan M, Calin GA, Zhang W, Lopez-Berestein G, Sood AK. Rupaimoole R, et al. Among authors: gharpure km. Nat Commun. 2014 Oct 29;5:5202. doi: 10.1038/ncomms6202. Nat Commun. 2014. PMID: 25351346 Free PMC article.
XPO1/CRM1 Inhibition Causes Antitumor Effects by Mitochondrial Accumulation of eIF5A.
Miyake T, Pradeep S, Wu SY, Rupaimoole R, Zand B, Wen Y, Gharpure KM, Nagaraja AS, Hu W, Cho MS, Dalton HJ, Previs RA, Taylor ML, Hisamatsu T, Kang Y, Liu T, Shacham S, McCauley D, Hawke DH, Wiktorowicz JE, Coleman RL, Sood AK. Miyake T, et al. Among authors: gharpure km. Clin Cancer Res. 2015 Jul 15;21(14):3286-97. doi: 10.1158/1078-0432.CCR-14-1953. Epub 2015 Apr 15. Clin Cancer Res. 2015. PMID: 25878333 Free PMC article.
Nanotechnology: Future of Oncotherapy.
Gharpure KM, Wu SY, Li C, Lopez-Berestein G, Sood AK. Gharpure KM, et al. Clin Cancer Res. 2015 Jul 15;21(14):3121-30. doi: 10.1158/1078-0432.CCR-14-1189. Clin Cancer Res. 2015. PMID: 26180057 Free PMC article. Review.
38 results