Chen TS - Search Results

1

A New Era for Cancer Target Therapies: Applying Systems Biology and Computer-Aided Drug Design to Cancer Therapies.

Wong YH, Chiu CC, Lin CL, Chen TS, Jheng BR, Lee YC, Chen J, Chen BS. Wong YH, et al. Among authors: chen j, chen bs, chen ts. Curr Pharm Biotechnol. 2016;17(14):1246-1267. doi: 10.2174/1389201017666161019160606. Curr Pharm Biotechnol. 2016. PMID: 27774890 Review.

2

Applying NGS Data to Find Evolutionary Network Biomarkers from the Early and Late Stages of Hepatocellular Carcinoma.

Wong YH, Wu CC, Lin CL, Chen TS, Chang TH, Chen BS. Wong YH, et al. Among authors: chen bs, chen ts. Biomed Res Int. 2015;2015:391475. doi: 10.1155/2015/391475. Epub 2015 Aug 20. Biomed Res Int. 2015. PMID: 26366411 Free PMC article.

3

Multiple target drug cocktail design for attacking the core network markers of four cancers using ligand-based and structure-based virtual screening methods.

Wong YH, Lin CL, Chen TS, Chen CA, Jiang PS, Lai YH, Chu L, Li CW, Chen JJ, Chen BS. Wong YH, et al. Among authors: chen jj, chen bs, chen ca, chen ts. BMC Med Genomics. 2015;8 Suppl 4(Suppl 4):S4. doi: 10.1186/1755-8794-8-S4-S4. Epub 2015 Dec 9. BMC Med Genomics. 2015. PMID: 26680552 Free PMC article.

4

Pharmacophore modeling and virtual screening to identify potential RET kinase inhibitors.

Shih KC, Shiau CW, Chen TS, Ko CH, Lin CL, Lin CY, Hwang CS, Tang CY, Chen WR, Huang JW. Shih KC, et al. Among authors: chen ts, chen wr. Bioorg Med Chem Lett. 2011 Aug 1;21(15):4490-7. doi: 10.1016/j.bmcl.2011.06.003. Epub 2011 Jun 12. Bioorg Med Chem Lett. 2011. PMID: 21724393

5

Selecting tyrosine kinase inhibitors for gastrointestinal stromal tumor with secondary KIT activation-loop domain mutations.

Hsueh YS, Lin CL, Chiang NJ, Yen CC, Li CF, Shan YS, Ko CH, Shih NY, Wang LM, Chen TS, Chen LT. Hsueh YS, et al. Among authors: chen ts, chen lt. PLoS One. 2013 Jun 20;8(6):e65762. doi: 10.1371/journal.pone.0065762. Print 2013. PLoS One. 2013. PMID: 23840364 Free PMC article.

6

Novel azulene-based derivatives as potent multi-receptor tyrosine kinase inhibitors.

Chen CH, Lee O, Yao CN, Chuang MY, Chang YL, Chang MH, Wen YF, Yang WH, Ko CH, Chou NT, Lin MW, Lai CP, Sun CY, Wang LM, Chen YC, Hseu TH, Chang CN, Hsu HC, Lin HC, Chang YL, Shih YC, Chou SH, Hsu YL, Tseng HW, Liu CP, Tu CM, Hu TL, Tsai YJ, Chen TS, Lin CL, Chiou SJ, Liu CC, Hwang CS. Chen CH, et al. Among authors: chen ts, chen yc. Bioorg Med Chem Lett. 2010 Oct 15;20(20):6129-32. doi: 10.1016/j.bmcl.2010.08.025. Epub 2010 Aug 10. Bioorg Med Chem Lett. 2010. PMID: 20833039

7

Design of novel FLT-3 inhibitors based on dual-layer 3D-QSAR model and fragment-based compounds in silico.

Shih KC, Lin CY, Chi HC, Hwang CS, Chen TS, Tang CY, Hsiao NW. Shih KC, et al. Among authors: chen ts. J Chem Inf Model. 2012 Jan 23;52(1):146-55. doi: 10.1021/ci200434f. Epub 2011 Dec 16. J Chem Inf Model. 2012. PMID: 22142286

8

Development of novel 3D-QSAR combination approach for screening and optimizing B-Raf inhibitors in silico.

Shih KC, Lin CY, Zhou J, Chi HC, Chen TS, Wang CC, Tseng HW, Tang CY. Shih KC, et al. Among authors: chen ts. J Chem Inf Model. 2011 Feb 28;51(2):398-407. doi: 10.1021/ci100351s. Epub 2010 Dec 23. J Chem Inf Model. 2011. PMID: 21182293

9

Action of Taiwan cobra cardiotoxin on membranes: binding modes of a beta-sheet polypeptide with phosphatidylcholine bilayers.

Sue SC, Rajan PK, Chen TS, Hsieh CH, Wu W. Sue SC, et al. Among authors: chen ts. Biochemistry. 1997 Aug 12;36(32):9826-36. doi: 10.1021/bi970413l. Biochemistry. 1997. PMID: 9245415

10

Structures of heparin-derived tetrasaccharide bound to cobra cardiotoxins: heparin binding at a single protein site with diverse side chain interactions.

Tjong SC, Chen TS, Huang WN, Wu WG. Tjong SC, et al. Among authors: chen ts. Biochemistry. 2007 Sep 4;46(35):9941-52. doi: 10.1021/bi700995v. Epub 2007 Aug 9. Biochemistry. 2007. PMID: 17685633

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