Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

11 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Junctophilin-2 gene therapy rescues heart failure by normalizing RyR2-mediated Ca2+ release.
Reynolds JO, Quick AP, Wang Q, Beavers DL, Philippen LE, Showell J, Barreto-Torres G, Thuerauf DJ, Doroudgar S, Glembotski CC, Wehrens XH. Reynolds JO, et al. Among authors: philippen le. Int J Cardiol. 2016 Dec 15;225:371-380. doi: 10.1016/j.ijcard.2016.10.021. Epub 2016 Oct 8. Int J Cardiol. 2016. PMID: 27760414 Free PMC article.
SPEG (Striated Muscle Preferentially Expressed Protein Kinase) Is Essential for Cardiac Function by Regulating Junctional Membrane Complex Activity.
Quick AP, Wang Q, Philippen LE, Barreto-Torres G, Chiang DY, Beavers D, Wang G, Khalid M, Reynolds JO, Campbell HM, Showell J, McCauley MD, Scholten A, Wehrens XH. Quick AP, et al. Among authors: philippen le. Circ Res. 2017 Jan 6;120(1):110-119. doi: 10.1161/CIRCRESAHA.116.309977. Epub 2016 Oct 11. Circ Res. 2017. PMID: 27729468 Free PMC article.
Novel junctophilin-2 mutation A405S is associated with basal septal hypertrophy and diastolic dysfunction.
Quick AP, Landstrom AP, Wang Q, Beavers DL, Reynolds JO, Barreto-Torres G, Tran V, Showell J, Philippen LE, Morris SA, Skapura D, Bos JM, Pedersen SE, Pautler RG, Ackerman MJ, Wehrens XH. Quick AP, et al. Among authors: philippen le. JACC Basic Transl Sci. 2017 Feb;2(1):56-67. doi: 10.1016/j.jacbts.2016.11.004. JACC Basic Transl Sci. 2017. PMID: 28393127 Free PMC article.
Atrial-Specific Gene Delivery Using an Adeno-Associated Viral Vector.
Ni L, Scott L Jr, Campbell HM, Pan X, Alsina KM, Reynolds J, Philippen LE, Hulsurkar M, Lagor WR, Li N, Wehrens XHT. Ni L, et al. Among authors: philippen le. Circ Res. 2019 Jan 18;124(2):256-262. doi: 10.1161/CIRCRESAHA.118.313811. Circ Res. 2019. PMID: 30582449 Free PMC article.
Therapeutic Delivery of miR-148a Suppresses Ventricular Dilation in Heart Failure.
Raso A, Dirkx E, Philippen LE, Fernandez-Celis A, De Majo F, Sampaio-Pinto V, Sansonetti M, Juni R, El Azzouzi H, Calore M, Bitsch N, Olieslagers S, Oerlemans MIFJ, Huibers MM, de Weger RA, Reckman YJ, Pinto YM, Zentilin L, Zacchigna S, Giacca M, da Costa Martins PA, López-Andrés N, De Windt LJ. Raso A, et al. Among authors: philippen le. Mol Ther. 2019 Mar 6;27(3):584-599. doi: 10.1016/j.ymthe.2018.11.011. Epub 2018 Nov 17. Mol Ther. 2019. PMID: 30559069 Free PMC article.
Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure.
Dirkx E, Gladka MM, Philippen LE, Armand AS, Kinet V, Leptidis S, El Azzouzi H, Salic K, Bourajjaj M, da Silva GJ, Olieslagers S, van der Nagel R, de Weger R, Bitsch N, Kisters N, Seyen S, Morikawa Y, Chanoine C, Heymans S, Volders PG, Thum T, Dimmeler S, Cserjesi P, Eschenhagen T, da Costa Martins PA, De Windt LJ. Dirkx E, et al. Among authors: philippen le. Nat Cell Biol. 2013 Nov;15(11):1282-93. doi: 10.1038/ncb2866. Epub 2013 Oct 27. Nat Cell Biol. 2013. PMID: 24161931
A novel miR-371a-5p-mediated pathway, leading to BAG3 upregulation in cardiomyocytes in response to epinephrine, is lost in Takotsubo cardiomyopathy.
d'Avenia M, Citro R, De Marco M, Veronese A, Rosati A, Visone R, Leptidis S, Philippen L, Vitale G, Cavallo A, Silverio A, Prota C, Gravina P, De Cola A, Carletti E, Coppola G, Gallo S, Provenza G, Bossone E, Piscione F, Hahne M, De Windt LJ, Turco MC, De Laurenzi V. d'Avenia M, et al. Cell Death Dis. 2015 Oct 29;6(10):e1948. doi: 10.1038/cddis.2015.280. Cell Death Dis. 2015. PMID: 26512958 Free PMC article.
11 results