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Mek1Y130C mice recapitulate aspects of human cardio-facio-cutaneous syndrome.
Aoidi R, Houde N, Landry-Truchon K, Holter M, Jacquet K, Charron L, Krishnaswami SR, Yu BD, Rauen KA, Bisson N, Newbern J, Charron J. Aoidi R, et al. Dis Model Mech. 2018 Mar 13;11(3):dmm031278. doi: 10.1242/dmm.031278. Dis Model Mech. 2018. PMID: 29590634 Free PMC article.
Fine-tuning of MEK signaling is pivotal for limiting B and T cell activation.
Houde N, Beuret L, Bonaud A, Fortier-Beaulieu SP, Truchon-Landry K, Aoidi R, Pic É, Alouche N, Rondeau V, Schlecht-Louf G, Balabanian K, Espéli M, Charron J. Houde N, et al. Among authors: aoidi r. Cell Rep. 2022 Jan 11;38(2):110223. doi: 10.1016/j.celrep.2021.110223. Cell Rep. 2022. PMID: 35021072 Free article.
Maternal iron deficiency perturbs embryonic cardiovascular development in mice.
Kalisch-Smith JI, Ved N, Szumska D, Munro J, Troup M, Harris SE, Rodriguez-Caro H, Jacquemot A, Miller JJ, Stuart EM, Wolna M, Hardman E, Prin F, Lana-Elola E, Aoidi R, Fisher EMC, Tybulewicz VLJ, Mohun TJ, Lakhal-Littleton S, De Val S, Giannoulatou E, Sparrow DB. Kalisch-Smith JI, et al. Among authors: aoidi r. Nat Commun. 2021 Jun 8;12(1):3447. doi: 10.1038/s41467-021-23660-5. Nat Commun. 2021. PMID: 34103494 Free PMC article.
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome.
Lana-Elola E, Aoidi R, Llorian M, Gibbins D, Buechsenschuetz C, Bussi C, Flynn H, Gilmore T, Watson-Scales S, Haugsten Hansen M, Hayward D, Song OR, Brault V, Herault Y, Deau E, Meijer L, Snijders AP, Gutierrez MG, Fisher EMC, Tybulewicz VLJ. Lana-Elola E, et al. Among authors: aoidi r. Sci Transl Med. 2024 Jan 24;16(731):eadd6883. doi: 10.1126/scitranslmed.add6883. Epub 2024 Jan 24. Sci Transl Med. 2024. PMID: 38266108 Free PMC article.