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Structural and conformational determinants of macrocycle cell permeability.
Over B, Matsson P, Tyrchan C, Artursson P, Doak BC, Foley MA, Hilgendorf C, Johnston SE, Lee MD 4th, Lewis RJ, McCarren P, Muncipinto G, Norinder U, Perry MW, Duvall JR, Kihlberg J. Over B, et al. Among authors: doak bc. Nat Chem Biol. 2016 Dec;12(12):1065-1074. doi: 10.1038/nchembio.2203. Epub 2016 Oct 17. Nat Chem Biol. 2016. PMID: 27748751
Cell permeability beyond the rule of 5.
Matsson P, Doak BC, Over B, Kihlberg J. Matsson P, et al. Among authors: doak bc. Adv Drug Deliv Rev. 2016 Jun 1;101:42-61. doi: 10.1016/j.addr.2016.03.013. Epub 2016 Apr 9. Adv Drug Deliv Rev. 2016. PMID: 27067608 Review.
Erratum: Structural and conformational determinants of macrocycle cell permeability.
Over B, Matsson P, Tyrchan C, Artursson P, Doak BC, Foley MA, Hilgendorf C, Johnston SE, Lee MD 4th, Lewis RJ, McCarren P, Muncipinto G, Norinder U, Perry MWD, Duvall JR, Kihlberg J. Over B, et al. Among authors: doak bc. Nat Chem Biol. 2017 Jul 18;13(8):922. doi: 10.1038/nchembio0817-922a. Nat Chem Biol. 2017. PMID: 28853740 No abstract available.
Cyclophilin Succumbs to a Macrocyclic Chameleon.
Doak BC, Kihlberg J. Doak BC, et al. J Med Chem. 2018 Nov 8;61(21):9469-9472. doi: 10.1021/acs.jmedchem.8b01555. Epub 2018 Oct 25. J Med Chem. 2018. PMID: 30359012
Drug Syntheses Beyond the Rule of 5.
Tyagi M, Begnini F, Poongavanam V, Doak BC, Kihlberg J. Tyagi M, et al. Among authors: doak bc. Chemistry. 2020 Jan 2;26(1):49-88. doi: 10.1002/chem.201902716. Epub 2019 Oct 11. Chemistry. 2020. PMID: 31483909 Review.
25 results