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Efficient Downregulation of Alk4 in Skeletal Muscle After Systemic Treatment with Conjugated siRNAs in a Mouse Model for Duchenne Muscular Dystrophy.
Engelbeen S, Pasteuning-Vuhman S, Boertje-van der Meulen J, Parmar R, Charisse K, Sepp-Lorenzino L, Manoharan M, Aartsma-Rus A, van Putten M. Engelbeen S, et al. Among authors: pasteuning vuhman s. Nucleic Acid Ther. 2023 Jan;33(1):26-34. doi: 10.1089/nat.2022.0021. Epub 2022 Oct 20. Nucleic Acid Ther. 2023. PMID: 36269327 Free PMC article.
New function of the myostatin/activin type I receptor (ALK4) as a mediator of muscle atrophy and muscle regeneration.
Pasteuning-Vuhman S, Boertje-van der Meulen JW, van Putten M, Overzier M, Ten Dijke P, Kiełbasa SM, Arindrarto W, Wolterbeek R, Lezhnina KV, Ozerov IV, Aliper AM, Hoogaars WM, Aartsma-Rus A, Loomans CJ. Pasteuning-Vuhman S, et al. FASEB J. 2017 Jan;31(1):238-255. doi: 10.1096/fj.201600675R. Epub 2016 Oct 12. FASEB J. 2017. PMID: 27733450 Free PMC article.