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Targeted Delivery of an Anti-inflammatory PDE4 Inhibitor to Immune Cells via an Antibody-drug Conjugate.
Yu S, Pearson AD, Lim RK, Rodgers DT, Li S, Parker HB, Weglarz M, Hampton EN, Bollong MJ, Shen J, Zambaldo C, Wang D, Woods AK, Wright TM, Schultz PG, Kazane SA, Young TS, Tremblay MS. Yu S, et al. Among authors: young ts. Mol Ther. 2016 Dec;24(12):2078-2089. doi: 10.1038/mt.2016.175. Epub 2016 Oct 12. Mol Ther. 2016. PMID: 27731313 Free PMC article.
Evolution of cyclic peptide protease inhibitors.
Young TS, Young DD, Ahmad I, Louis JM, Benkovic SJ, Schultz PG. Young TS, et al. Among authors: young dd. Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11052-6. doi: 10.1073/pnas.1108045108. Epub 2011 Jun 20. Proc Natl Acad Sci U S A. 2011. PMID: 21690365 Free PMC article.
Ribosomal route to small-molecule diversity.
Tianero MD, Donia MS, Young TS, Schultz PG, Schmidt EW. Tianero MD, et al. Among authors: young ts. J Am Chem Soc. 2012 Jan 11;134(1):418-25. doi: 10.1021/ja208278k. Epub 2011 Dec 22. J Am Chem Soc. 2012. PMID: 22107593 Free PMC article.
An immunosuppressive antibody-drug conjugate.
Wang RE, Liu T, Wang Y, Cao Y, Du J, Luo X, Deshmukh V, Kim CH, Lawson BR, Tremblay MS, Young TS, Kazane SA, Wang F, Schultz PG. Wang RE, et al. Among authors: young ts. J Am Chem Soc. 2015 Mar 11;137(9):3229-32. doi: 10.1021/jacs.5b00620. Epub 2015 Feb 27. J Am Chem Soc. 2015. PMID: 25699419 Free PMC article.
43 results