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Indirubin derivatives: a patent review (2010 - present).
Gaboriaud-Kolar N, Vougogiannopoulou K, Skaltsounis AL. Gaboriaud-Kolar N, et al. Among authors: vougogiannopoulou k. Expert Opin Ther Pat. 2015 May;25(5):583-93. doi: 10.1517/13543776.2015.1019865. Expert Opin Ther Pat. 2015. PMID: 25887337 Review.
Indirubin derivatives are potent and selective anti-Trypanosoma cruzi agents.
Efstathiou A, Meira CS, Gaboriaud-Kolar N, Bastos TM, Rocha VPC, Vougogiannopoulou K, Skaltsounis AL, Smirlis D, Soares MBP. Efstathiou A, et al. Among authors: vougogiannopoulou k. Virulence. 2018;9(1):1658-1668. doi: 10.1080/21505594.2018.1532242. Virulence. 2018. PMID: 30387370 Free PMC article.
Indirubin Analogues Inhibit Trypanosoma brucei Glycogen Synthase Kinase 3 Short and T. brucei Growth.
Efstathiou A, Gaboriaud-Kolar N, Myrianthopoulos V, Vougogiannopoulou K, Subota I, Aicher S, Mikros E, Bastin P, Skaltsounis AL, Soteriadou K, Smirlis D. Efstathiou A, et al. Among authors: vougogiannopoulou k. Antimicrob Agents Chemother. 2019 May 24;63(6):e02065-18. doi: 10.1128/AAC.02065-18. Print 2019 Jun. Antimicrob Agents Chemother. 2019. PMID: 30910902 Free PMC article.
An inhibitor-driven study for enhancing the selectivity of indirubin derivatives towards leishmanial Glycogen Synthase Kinase-3 over leishmanial cdc2-related protein kinase 3.
Efstathiou A, Gaboriaud-Kolar N, Smirlis D, Myrianthopoulos V, Vougogiannopoulou K, Alexandratos A, Kritsanida M, Mikros E, Soteriadou K, Skaltsounis AL. Efstathiou A, et al. Among authors: vougogiannopoulou k. Parasit Vectors. 2014 May 20;7:234. doi: 10.1186/1756-3305-7-234. Parasit Vectors. 2014. PMID: 24886176 Free PMC article.
From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity.
Durieu E, Prina E, Leclercq O, Oumata N, Gaboriaud-Kolar N, Vougogiannopoulou K, Aulner N, Defontaine A, No JH, Ruchaud S, Skaltsounis AL, Galons H, Späth GF, Meijer L, Rachidi N. Durieu E, et al. Among authors: vougogiannopoulou k. Antimicrob Agents Chemother. 2016 Apr 22;60(5):2822-33. doi: 10.1128/AAC.00021-16. Print 2016 May. Antimicrob Agents Chemother. 2016. PMID: 26902771 Free PMC article.
The indirubin derivative 6-bromoindirubin-3'-glycerol-oxime ether (6BIGOE) potently modulates inflammatory cytokine and prostaglandin release from human monocytes through GSK-3 interference.
Czapka A, König S, Pergola C, Grune C, Vougogiannopoulou K, Skaltsounis AL, Fischer D, Werz O. Czapka A, et al. Among authors: vougogiannopoulou k. Biochem Pharmacol. 2020 Oct;180:114170. doi: 10.1016/j.bcp.2020.114170. Epub 2020 Jul 22. Biochem Pharmacol. 2020. PMID: 32710971
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