Skaltsounis AL - Search Results

1

Natural-Based Indirubins Display Potent Cytotoxicity toward Wild-Type and T315I-Resistant Leukemia Cell Lines.

Gaboriaud-Kolar N, Myrianthopoulos V, Vougogiannopoulou K, Gerolymatos P, Horne DA, Jove R, Mikros E, Nam S, Skaltsounis AL. Gaboriaud-Kolar N, et al. Among authors: skaltsounis al. J Nat Prod. 2016 Oct 28;79(10):2464-2471. doi: 10.1021/acs.jnatprod.6b00285. Epub 2016 Oct 11. J Nat Prod. 2016. PMID: 27726390 Free PMC article.

2

Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases.

Polychronopoulos P, Magiatis P, Skaltsounis AL, Myrianthopoulos V, Mikros E, Tarricone A, Musacchio A, Roe SM, Pearl L, Leost M, Greengard P, Meijer L. Polychronopoulos P, et al. Among authors: skaltsounis al. J Med Chem. 2004 Feb 12;47(4):935-46. doi: 10.1021/jm031016d. J Med Chem. 2004. PMID: 14761195

3

An integrated computational approach to the phenomenon of potent and selective inhibition of aurora kinases B and C by a series of 7-substituted indirubins.

Myrianthopoulos V, Magiatis P, Ferandin Y, Skaltsounis AL, Meijer L, Mikros E. Myrianthopoulos V, et al. Among authors: skaltsounis al. J Med Chem. 2007 Aug 23;50(17):4027-37. doi: 10.1021/jm070077z. Epub 2007 Aug 1. J Med Chem. 2007. PMID: 17665890

4

Soluble 3',6-substituted indirubins with enhanced selectivity toward glycogen synthase kinase -3 alter circadian period.

Vougogiannopoulou K, Ferandin Y, Bettayeb K, Myrianthopoulos V, Lozach O, Fan Y, Johnson CH, Magiatis P, Skaltsounis AL, Mikros E, Meijer L. Vougogiannopoulou K, et al. Among authors: skaltsounis al. J Med Chem. 2008 Oct 23;51(20):6421-31. doi: 10.1021/jm800648y. Epub 2008 Sep 25. J Med Chem. 2008. PMID: 18816110 Free PMC article.

5

6-Br-5methylindirubin-3'oxime (5-Me-6-BIO) targeting the leishmanial glycogen synthase kinase-3 (GSK-3) short form affects cell-cycle progression and induces apoptosis-like death: exploitation of GSK-3 for treating leishmaniasis.

Xingi E, Smirlis D, Myrianthopoulos V, Magiatis P, Grant KM, Meijer L, Mikros E, Skaltsounis AL, Soteriadou K. Xingi E, et al. Among authors: skaltsounis al. Int J Parasitol. 2009 Oct;39(12):1289-303. doi: 10.1016/j.ijpara.2009.04.005. Epub 2009 May 13. Int J Parasitol. 2009. PMID: 19445946

6

The raputindoles: novel cyclopentyl bisindole alkaloids from Raputia simulans.

Vougogiannopoulou K, Fokialakis N, Aligiannis N, Cantrell C, Skaltsounis AL. Vougogiannopoulou K, et al. Among authors: skaltsounis al. Org Lett. 2010 May 7;12(9):1908-11. doi: 10.1021/ol100584w. Org Lett. 2010. PMID: 20394392

7

Simple indole alkaloids from the neotropical rutaceous tree Raputia simulans.

Vougogiannopoulou K, Fokialakis N, Aligiannis N, Cantrell C, Skaltsounis AL. Vougogiannopoulou K, et al. Among authors: skaltsounis al. Planta Med. 2011 Sep;77(13):1559-61. doi: 10.1055/s-0030-1270850. Epub 2011 Mar 7. Planta Med. 2011. PMID: 21384318

8

(WO2011057959) indole and indazole derivatives as glycogen synthase activators: a patent evaluation.

Skaltsounis AL, Gaboriaud-Kolar N. Skaltsounis AL, et al. Expert Opin Ther Pat. 2011 Dec;21(12):1925-9. doi: 10.1517/13543776.2011.625406. Epub 2011 Oct 12. Expert Opin Ther Pat. 2011. PMID: 21988345 Review.

9

Cytotoxic prenylated acetophenone dimers from Acronychia pedunculata.

Kouloura E, Halabalaki M, Lallemand MC, Nam S, Jove R, Litaudon M, Awang K, Hadi HA, Skaltsounis AL. Kouloura E, et al. Among authors: skaltsounis al. J Nat Prod. 2012 Jul 27;75(7):1270-6. doi: 10.1021/np201007a. Epub 2012 Jun 18. J Nat Prod. 2012. PMID: 22708987

10

Synthesis and in vitro biological evaluation of novel pyrazole derivatives as potential antitumor agents.

Christodoulou MS, Fokialakis N, Nam S, Jove R, Skaltsounis AL, Haroutounian SA. Christodoulou MS, et al. Among authors: skaltsounis al. Med Chem. 2012 Sep;8(5):779-88. doi: 10.2174/157340612802084252. Med Chem. 2012. PMID: 22741785

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