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The Impact of the Gut Microbiota on Drug Metabolism and Clinical Outcome.
Yale J Biol Med. 2016 Sep 30;89(3):375-382. eCollection 2016 Sep.
Yale J Biol Med. 2016.
PMID: 27698621
Free PMC article.
Review.
Impact of Gut Microbiota-Mediated Bile Acid Metabolism on the Solubilization Capacity of Bile Salt Micelles and Drug Solubility.
Enright EF, Joyce SA, Gahan CG, Griffin BT.
Enright EF, et al.
Mol Pharm. 2017 Apr 3;14(4):1251-1263. doi: 10.1021/acs.molpharmaceut.6b01155. Epub 2017 Feb 24.
Mol Pharm. 2017.
PMID: 28186768
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Gut Microbiota-Mediated Bile Acid Transformations Alter the Cellular Response to Multidrug Resistant Transporter Substrates in Vitro: Focus on P-glycoprotein.
Enright EF, Govindarajan K, Darrer R, MacSharry J, Joyce SA, Gahan CGM.
Enright EF, et al.
Mol Pharm. 2018 Dec 3;15(12):5711-5727. doi: 10.1021/acs.molpharmaceut.8b00875. Epub 2018 Nov 16.
Mol Pharm. 2018.
PMID: 30388019
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Microbiome-mediated bile acid modification: Role in intestinal drug absorption and metabolism.
Enright EF, Griffin BT, Gahan CGM, Joyce SA.
Enright EF, et al.
Pharmacol Res. 2018 Jul;133:170-186. doi: 10.1016/j.phrs.2018.04.009. Epub 2018 Apr 13.
Pharmacol Res. 2018.
PMID: 29660405
Review.
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Impact of phospholipid digests and bile acid pool variations on the crystallization of atazanavir from supersaturated solutions.
Enright EF, Joyce SA, Gahan CGM, Taylor LS.
Enright EF, et al.
Eur J Pharm Biopharm. 2020 Aug;153:68-83. doi: 10.1016/j.ejpb.2020.05.022. Epub 2020 May 27.
Eur J Pharm Biopharm. 2020.
PMID: 32473291
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