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Targeting the Bone Marrow Microenvironment.
Moschetta M, Kawano Y, Podar K. Moschetta M, et al. Cancer Treat Res. 2016;169:63-102. doi: 10.1007/978-3-319-40320-5_6. Cancer Treat Res. 2016. PMID: 27696259 Review.
Lenalidomide restrains motility and overangiogenic potential of bone marrow endothelial cells in patients with active multiple myeloma.
De Luisi A, Ferrucci A, Coluccia AM, Ria R, Moschetta M, de Luca E, Pieroni L, Maffia M, Urbani A, Di Pietro G, Guarini A, Ranieri G, Ditonno P, Berardi S, Caivano A, Basile A, Cascavilla N, Capalbo S, Quarta G, Dammacco F, Ribatti D, Vacca A. De Luisi A, et al. Among authors: moschetta m. Clin Cancer Res. 2011 Apr 1;17(7):1935-46. doi: 10.1158/1078-0432.CCR-10-2381. Epub 2011 Feb 9. Clin Cancer Res. 2011. PMID: 21307145
HIF-1α of bone marrow endothelial cells implies relapse and drug resistance in patients with multiple myeloma and may act as a therapeutic target.
Ria R, Catacchio I, Berardi S, De Luisi A, Caivano A, Piccoli C, Ruggieri V, Frassanito MA, Ribatti D, Nico B, Annese T, Ruggieri S, Guarini A, Minoia C, Ditonno P, Angelucci E, Derudas D, Moschetta M, Dammacco F, Vacca A. Ria R, et al. Among authors: moschetta m. Clin Cancer Res. 2014 Feb 15;20(4):847-58. doi: 10.1158/1078-0432.CCR-13-1950. Epub 2013 Dec 2. Clin Cancer Res. 2014. PMID: 24297864
Engineered nanomedicine for myeloma and bone microenvironment targeting.
Swami A, Reagan MR, Basto P, Mishima Y, Kamaly N, Glavey S, Zhang S, Moschetta M, Seevaratnam D, Zhang Y, Liu J, Memarzadeh M, Wu J, Manier S, Shi J, Bertrand N, Lu ZN, Nagano K, Baron R, Sacco A, Roccaro AM, Farokhzad OC, Ghobrial IM. Swami A, et al. Among authors: moschetta m. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10287-92. doi: 10.1073/pnas.1401337111. Epub 2014 Jun 30. Proc Natl Acad Sci U S A. 2014. PMID: 24982170 Free PMC article.
A HGF/cMET autocrine loop is operative in multiple myeloma bone marrow endothelial cells and may represent a novel therapeutic target.
Ferrucci A, Moschetta M, Frassanito MA, Berardi S, Catacchio I, Ria R, Racanelli V, Caivano A, Solimando AG, Vergara D, Maffia M, Latorre D, Rizzello A, Zito A, Ditonno P, Maiorano E, Ribatti D, Vacca A. Ferrucci A, et al. Among authors: moschetta m. Clin Cancer Res. 2014 Nov 15;20(22):5796-807. doi: 10.1158/1078-0432.CCR-14-0847. Epub 2014 Sep 11. Clin Cancer Res. 2014. PMID: 25212607
SDF-1 inhibition targets the bone marrow niche for cancer therapy.
Roccaro AM, Sacco A, Purschke WG, Moschetta M, Buchner K, Maasch C, Zboralski D, Zöllner S, Vonhoff S, Mishima Y, Maiso P, Reagan MR, Lonardi S, Ungari M, Facchetti F, Eulberg D, Kruschinski A, Vater A, Rossi G, Klussmann S, Ghobrial IM. Roccaro AM, et al. Among authors: moschetta m. Cell Rep. 2014 Oct 9;9(1):118-128. doi: 10.1016/j.celrep.2014.08.042. Epub 2014 Sep 25. Cell Rep. 2014. PMID: 25263552 Free PMC article.
Targeting the bone marrow microenvironment in multiple myeloma.
Kawano Y, Moschetta M, Manier S, Glavey S, Görgün GT, Roccaro AM, Anderson KC, Ghobrial IM. Kawano Y, et al. Among authors: moschetta m. Immunol Rev. 2015 Jan;263(1):160-72. doi: 10.1111/imr.12233. Immunol Rev. 2015. PMID: 25510276 Review.
The cancer glycome: carbohydrates as mediators of metastasis.
Glavey SV, Huynh D, Reagan MR, Manier S, Moschetta M, Kawano Y, Roccaro AM, Ghobrial IM, Joshi L, O'Dwyer ME. Glavey SV, et al. Among authors: moschetta m. Blood Rev. 2015 Jul;29(4):269-79. doi: 10.1016/j.blre.2015.01.003. Epub 2015 Jan 23. Blood Rev. 2015. PMID: 25636501 Review.
236 results