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Interleukin-13 immune gene therapy prevents CNS inflammation and demyelination via alternative activation of microglia and macrophages.
Guglielmetti C, Le Blon D, Santermans E, Salas-Perdomo A, Daans J, De Vocht N, Shah D, Hoornaert C, Praet J, Peerlings J, Kara F, Bigot C, Mai Z, Goossens H, Hens N, Hendrix S, Verhoye M, Planas AM, Berneman Z, van der Linden A, Ponsaerts P. Guglielmetti C, et al. Among authors: santermans e. Glia. 2016 Dec;64(12):2181-2200. doi: 10.1002/glia.23053. Epub 2016 Sep 29. Glia. 2016. PMID: 27685637
Early Inflammatory Responses Following Cell Grafting in the CNS Trigger Activation of the Subventricular Zone: A Proposed Model of Sequential Cellular Events.
Praet J, Santermans E, Daans J, Le Blon D, Hoornaert C, Goossens H, Hens N, Van der Linden A, Berneman Z, Ponsaerts P. Praet J, et al. Among authors: santermans e. Cell Transplant. 2015;24(8):1481-92. doi: 10.3727/096368914X682800. Epub 2014 Jul 14. Cell Transplant. 2015. PMID: 25197881 Free article.
Intracerebral transplantation of interleukin 13-producing mesenchymal stem cells limits microgliosis, oligodendrocyte loss and demyelination in the cuprizone mouse model.
Le Blon D, Guglielmetti C, Hoornaert C, Quarta A, Daans J, Dooley D, Lemmens E, Praet J, De Vocht N, Reekmans K, Santermans E, Hens N, Goossens H, Verhoye M, Van der Linden A, Berneman Z, Hendrix S, Ponsaerts P. Le Blon D, et al. Among authors: santermans e. J Neuroinflammation. 2016 Nov 9;13(1):288. doi: 10.1186/s12974-016-0756-7. J Neuroinflammation. 2016. PMID: 27829467 Free PMC article.
Histological characterization and quantification of cellular events following neural and fibroblast(-like) stem cell grafting in healthy and demyelinated CNS tissue.
Praet J, Santermans E, Reekmans K, de Vocht N, Le Blon D, Hoornaert C, Daans J, Goossens H, Berneman Z, Hens N, Van der Linden A, Ponsaerts P. Praet J, et al. Among authors: santermans e. Methods Mol Biol. 2014;1213:265-83. doi: 10.1007/978-1-4939-1453-1_22. Methods Mol Biol. 2014. PMID: 25173390
Distinct in vitro properties of embryonic and extraembryonic fibroblast-like cells are reflected in their in vivo behavior following grafting in the adult mouse brain.
Costa R, Bergwerf I, Santermans E, De Vocht N, Praet J, Daans J, Le Blon D, Hoornaert C, Reekmans K, Hens N, Goossens H, Berneman Z, Parolini O, Alviano F, Ponsaerts P. Costa R, et al. Among authors: santermans e. Cell Transplant. 2015;24(2):223-33. doi: 10.3727/096368913X676196. Epub 2013 Dec 30. Cell Transplant. 2015. PMID: 24380384 Free article.
22 results