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Interleukin-13 immune gene therapy prevents CNS inflammation and demyelination via alternative activation of microglia and macrophages.
Guglielmetti C, Le Blon D, Santermans E, Salas-Perdomo A, Daans J, De Vocht N, Shah D, Hoornaert C, Praet J, Peerlings J, Kara F, Bigot C, Mai Z, Goossens H, Hens N, Hendrix S, Verhoye M, Planas AM, Berneman Z, van der Linden A, Ponsaerts P. Guglielmetti C, et al. Among authors: salas perdomo a. Glia. 2016 Dec;64(12):2181-2200. doi: 10.1002/glia.23053. Epub 2016 Sep 29. Glia. 2016. PMID: 27685637
Combined treatment with recombinant tissue plasminogen activator and dexamethasone phosphate-containing liposomes improves neurological outcome and restricts lesion progression after embolic stroke in rats.
Tiebosch IA, Crielaard BJ, Bouts MJ, Zwartbol R, Salas-Perdomo A, Lammers T, Planas AM, Storm G, Dijkhuizen RM. Tiebosch IA, et al. J Neurochem. 2012 Nov;123 Suppl 2:65-74. doi: 10.1111/j.1471-4159.2012.07945.x. J Neurochem. 2012. PMID: 23050644 Free article.
In vivo imaging of induction of heat-shock protein-70 gene expression with fluorescence reflectance imaging and intravital confocal microscopy following brain ischaemia in reporter mice.
de la Rosa X, Santalucía T, Fortin PY, Purroy J, Calvo M, Salas-Perdomo A, Justicia C, Couillaud F, Planas AM. de la Rosa X, et al. Eur J Nucl Med Mol Imaging. 2013 Feb;40(3):426-38. doi: 10.1007/s00259-012-2277-7. Epub 2012 Nov 8. Eur J Nucl Med Mol Imaging. 2013. PMID: 23135322 Free article.
Results of a preclinical randomized controlled multicenter trial (pRCT): Anti-CD49d treatment for acute brain ischemia.
Llovera G, Hofmann K, Roth S, Salas-Pérdomo A, Ferrer-Ferrer M, Perego C, Zanier ER, Mamrak U, Rex A, Party H, Agin V, Fauchon C, Orset C, Haelewyn B, De Simoni MG, Dirnagl U, Grittner U, Planas AM, Plesnila N, Vivien D, Liesz A. Llovera G, et al. Sci Transl Med. 2015 Aug 5;7(299):299ra121. doi: 10.1126/scitranslmed.aaa9853. Sci Transl Med. 2015. PMID: 26246166
Uric Acid Is Protective After Cerebral Ischemia/Reperfusion in Hyperglycemic Mice.
Justicia C, Salas-Perdomo A, Pérez-de-Puig I, Deddens LH, van Tilborg GAF, Castellví C, Dijkhuizen RM, Chamorro Á, Planas AM. Justicia C, et al. Among authors: salas perdomo a. Transl Stroke Res. 2017 Jun;8(3):294-305. doi: 10.1007/s12975-016-0515-1. Epub 2016 Dec 15. Transl Stroke Res. 2017. PMID: 27981484
T Cells Prevent Hemorrhagic Transformation in Ischemic Stroke by P-Selectin Binding.
Salas-Perdomo A, Miró-Mur F, Urra X, Justicia C, Gallizioli M, Zhao Y, Brait VH, Laredo C, Tudela R, Hidalgo A, Chamorro Á, Planas AM. Salas-Perdomo A, et al. Arterioscler Thromb Vasc Biol. 2018 Aug;38(8):1761-1771. doi: 10.1161/ATVBAHA.118.311284. Arterioscler Thromb Vasc Biol. 2018. PMID: 29903733
CNS-border associated macrophages respond to acute ischemic stroke attracting granulocytes and promoting vascular leakage.
Pedragosa J, Salas-Perdomo A, Gallizioli M, Cugota R, Miró-Mur F, Briansó F, Justicia C, Pérez-Asensio F, Marquez-Kisinousky L, Urra X, Gieryng A, Kaminska B, Chamorro A, Planas AM. Pedragosa J, et al. Among authors: salas perdomo a. Acta Neuropathol Commun. 2018 Aug 9;6(1):76. doi: 10.1186/s40478-018-0581-6. Acta Neuropathol Commun. 2018. PMID: 30092836 Free PMC article.
Microglial cell loss after ischemic stroke favors brain neutrophil accumulation.
Otxoa-de-Amezaga A, Miró-Mur F, Pedragosa J, Gallizioli M, Justicia C, Gaja-Capdevila N, Ruíz-Jaen F, Salas-Perdomo A, Bosch A, Calvo M, Márquez-Kisinousky L, Denes A, Gunzer M, Planas AM. Otxoa-de-Amezaga A, et al. Among authors: salas perdomo a. Acta Neuropathol. 2019 Feb;137(2):321-341. doi: 10.1007/s00401-018-1954-4. Epub 2018 Dec 22. Acta Neuropathol. 2019. PMID: 30580383 Free PMC article.
15 results