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Interleukin-13 immune gene therapy prevents CNS inflammation and demyelination via alternative activation of microglia and macrophages.
Guglielmetti C, Le Blon D, Santermans E, Salas-Perdomo A, Daans J, De Vocht N, Shah D, Hoornaert C, Praet J, Peerlings J, Kara F, Bigot C, Mai Z, Goossens H, Hens N, Hendrix S, Verhoye M, Planas AM, Berneman Z, van der Linden A, Ponsaerts P. Guglielmetti C, et al. Among authors: planas am. Glia. 2016 Dec;64(12):2181-2200. doi: 10.1002/glia.23053. Epub 2016 Sep 29. Glia. 2016. PMID: 27685637
Induction of COX-2 enzyme and down-regulation of COX-1 expression by lipopolysaccharide (LPS) control prostaglandin E2 production in astrocytes.
Font-Nieves M, Sans-Fons MG, Gorina R, Bonfill-Teixidor E, Salas-Pérdomo A, Márquez-Kisinousky L, Santalucia T, Planas AM. Font-Nieves M, et al. Among authors: planas am. J Biol Chem. 2012 Feb 24;287(9):6454-68. doi: 10.1074/jbc.M111.327874. Epub 2012 Jan 4. J Biol Chem. 2012. PMID: 22219191 Free PMC article.
Combined treatment with recombinant tissue plasminogen activator and dexamethasone phosphate-containing liposomes improves neurological outcome and restricts lesion progression after embolic stroke in rats.
Tiebosch IA, Crielaard BJ, Bouts MJ, Zwartbol R, Salas-Perdomo A, Lammers T, Planas AM, Storm G, Dijkhuizen RM. Tiebosch IA, et al. Among authors: planas am. J Neurochem. 2012 Nov;123 Suppl 2:65-74. doi: 10.1111/j.1471-4159.2012.07945.x. J Neurochem. 2012. PMID: 23050644 Free article.
In vivo imaging of induction of heat-shock protein-70 gene expression with fluorescence reflectance imaging and intravital confocal microscopy following brain ischaemia in reporter mice.
de la Rosa X, Santalucía T, Fortin PY, Purroy J, Calvo M, Salas-Perdomo A, Justicia C, Couillaud F, Planas AM. de la Rosa X, et al. Among authors: planas am. Eur J Nucl Med Mol Imaging. 2013 Feb;40(3):426-38. doi: 10.1007/s00259-012-2277-7. Epub 2012 Nov 8. Eur J Nucl Med Mol Imaging. 2013. PMID: 23135322 Free article.
Results of a preclinical randomized controlled multicenter trial (pRCT): Anti-CD49d treatment for acute brain ischemia.
Llovera G, Hofmann K, Roth S, Salas-Pérdomo A, Ferrer-Ferrer M, Perego C, Zanier ER, Mamrak U, Rex A, Party H, Agin V, Fauchon C, Orset C, Haelewyn B, De Simoni MG, Dirnagl U, Grittner U, Planas AM, Plesnila N, Vivien D, Liesz A. Llovera G, et al. Among authors: planas am. Sci Transl Med. 2015 Aug 5;7(299):299ra121. doi: 10.1126/scitranslmed.aaa9853. Sci Transl Med. 2015. PMID: 26246166
252 results