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A Tetravalent Formulation Based on Recombinant Nucleocapsid-like Particles from Dengue Viruses Induces a Functional Immune Response in Mice and Monkeys.
Gil L, Cobas K, Lazo L, Marcos E, Hernández L, Suzarte E, Izquierdo A, Valdés I, Blanco A, Puentes P, Romero Y, Pérez Y, Guzmán MG, Guillén G, Hermida L. Gil L, et al. Among authors: guzman mg. J Immunol. 2016 Nov 1;197(9):3597-3606. doi: 10.4049/jimmunol.1600927. Epub 2016 Sep 28. J Immunol. 2016. PMID: 27683751
The protein DIIIC-2, aggregated with a specific oligodeoxynucleotide and adjuvanted in alum, protects mice and monkeys against DENV-2.
Gil L, Marcos E, Izquierdo A, Lazo L, Valdés I, Ambala P, Ochola L, Hitler R, Suzarte E, Álvarez M, Kimiti P, Ndung'u J, Kariuki T, Guzmán MG, Guillén G, Hermida L. Gil L, et al. Among authors: guzman mg. Immunol Cell Biol. 2015 Jan;93(1):57-66. doi: 10.1038/icb.2014.63. Epub 2014 Sep 2. Immunol Cell Biol. 2015. PMID: 25178969
A fragment of the envelope protein from dengue-1 virus, fused in two different sites of the meningococcal P64k protein carrier, induces a functional immune response in mice.
Hermida L, Rodríguez R, Lazo L, Bernardo L, Silva R, Zulueta A, López C, Martín J, Valdés I, del Rosario D, Guillén G, Guzmán MG. Hermida L, et al. Among authors: guzman mg. Biotechnol Appl Biochem. 2004 Feb;39(Pt 1):107-14. doi: 10.1042/BA20030039. Biotechnol Appl Biochem. 2004. PMID: 12887334
Viremia and antibody response in green monkeys (Chlorocebus aethiops sabaeus) infected with dengue virus type 2: a potential model for vaccine testing.
Martín J, Hermida L, Castro J, Lazo L, Martínez R, Gil L, Romero Y, Puente P, Zaragoza S, Cosme K, Guzmán MG, Cardosa J, Guillén G. Martín J, et al. Among authors: guzman mg. Microbiol Immunol. 2009 Apr;53(4):216-23. doi: 10.1111/j.1348-0421.2009.00112.x. Microbiol Immunol. 2009. PMID: 19714858 Free article.
Heterologous prime-boost strategy in non-human primates combining the infective dengue virus and a recombinant protein in a formulation suitable for human use.
Valdés I, Hermida L, Gil L, Lazo L, Castro J, Martín J, Bernardo L, López C, Niebla O, Menéndez T, Romero Y, Sánchez J, Guzmán MG, Guillén G. Valdés I, et al. Among authors: guzman mg. Int J Infect Dis. 2010 May;14(5):e377-83. doi: 10.1016/j.ijid.2009.06.017. Epub 2009 Sep 20. Int J Infect Dis. 2010. PMID: 19773190 Free article.
A novel fusion protein domain III-capsid from dengue-2, in a highly aggregated form, induces a functional immune response and protection in mice.
Valdés I, Bernardo L, Gil L, Pavón A, Lazo L, López C, Romero Y, Menendez I, Falcón V, Betancourt L, Martín J, Chinea G, Silva R, Guzmán MG, Guillén G, Hermida L. Valdés I, et al. Among authors: guzman mg. Virology. 2009 Nov 25;394(2):249-58. doi: 10.1016/j.virol.2009.08.029. Epub 2009 Sep 23. Virology. 2009. PMID: 19783271 Free article.
236 results