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Platform model describing pharmacokinetic properties of vc-MMAE antibody-drug conjugates.
Kågedal M, Gibiansky L, Xu J, Wang X, Samineni D, Chen SC, Lu D, Agarwal P, Wang B, Saad O, Koppada N, Fine BM, Jin JY, Girish S, Li C. Kågedal M, et al. Among authors: wang x, wang b. J Pharmacokinet Pharmacodyn. 2017 Dec;44(6):537-548. doi: 10.1007/s10928-017-9544-y. Epub 2017 Sep 16. J Pharmacokinet Pharmacodyn. 2017. PMID: 28918591
Prediction of Human Pharmacokinetics of Antibody-Drug Conjugates From Nonclinical Data.
Li C, Zhang C, Deng R, Leipold D, Li D, Latifi B, Gao Y, Zhang C, Li Z, Miles D, Chen SC, Samineni D, Wang B, Agarwal P, Lu D, Prabhu S, Girish S, Kamath AV. Li C, et al. Among authors: wang b. Clin Transl Sci. 2019 Sep;12(5):534-544. doi: 10.1111/cts.12649. Epub 2019 Jun 11. Clin Transl Sci. 2019. PMID: 31115997 Free PMC article.
Clinical pharmacology of trastuzumab emtansine (T-DM1): an antibody-drug conjugate in development for the treatment of HER2-positive cancer.
Girish S, Gupta M, Wang B, Lu D, Krop IE, Vogel CL, Burris Iii HA, LoRusso PM, Yi JH, Saad O, Tong B, Chu YW, Holden S, Joshi A. Girish S, et al. Among authors: wang b. Cancer Chemother Pharmacol. 2012 May;69(5):1229-40. doi: 10.1007/s00280-011-1817-3. Epub 2012 Jan 20. Cancer Chemother Pharmacol. 2012. PMID: 22271209 Free PMC article. Clinical Trial.
Phase I Study of DSTP3086S, an Antibody-Drug Conjugate Targeting Six-Transmembrane Epithelial Antigen of Prostate 1, in Metastatic Castration-Resistant Prostate Cancer.
Danila DC, Szmulewitz RZ, Vaishampayan U, Higano CS, Baron AD, Gilbert HN, Brunstein F, Milojic-Blair M, Wang B, Kabbarah O, Mamounas M, Fine BM, Maslyar DJ, Ungewickell A, Scher HI. Danila DC, et al. Among authors: wang b. J Clin Oncol. 2019 Dec 20;37(36):3518-3527. doi: 10.1200/JCO.19.00646. Epub 2019 Nov 5. J Clin Oncol. 2019. PMID: 31689155 Free PMC article. Clinical Trial.
Pharmacokinetics and Exposure-Response Analysis of Venetoclax + Obinutuzumab in Chronic Lymphocytic Leukemia: Phase 1b Study and Phase 3 CLL14 Trial.
Samineni D, Gibiansky L, Wang B, Vadhavkar S, Rajwanshi R, Tandon M, Sinha A, Al-Sawaf O, Fischer K, Hallek M, Salem AH, Li C, Miles D. Samineni D, et al. Among authors: wang b. Adv Ther. 2022 Aug;39(8):3635-3653. doi: 10.1007/s12325-022-02170-w. Epub 2022 Jun 16. Adv Ther. 2022. PMID: 35708885 Free PMC article. Clinical Trial.
Effects of Trastuzumab Emtansine (T-DM1) on QT Interval and Safety of Pertuzumab Plus T-DM1 in Patients With Previously Treated Human Epidermal Growth Factor Receptor 2-Positive Metastatic Breast Cancer.
Gupta M, Wang B, Carrothers TJ, LoRusso PM, Chu YW, Shih T, Loecke D, Joshi A, Saad O, Yi JH, Girish S. Gupta M, et al. Among authors: wang b. Clin Pharmacol Drug Dev. 2013 Jan;2(1):11-24. doi: 10.1002/cpdd.9. Epub 2013 Feb 26. Clin Pharmacol Drug Dev. 2013. PMID: 27121556
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