Gottlieb E - Search Results

1

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.

Mills EL, Kelly B, Logan A, Costa ASH, Varma M, Bryant CE, Tourlomousis P, Däbritz JHM, Gottlieb E, Latorre I, Corr SC, McManus G, Ryan D, Jacobs HT, Szibor M, Xavier RJ, Braun T, Frezza C, Murphy MP, O'Neill LA. Mills EL, et al. Among authors: gottlieb e. Cell. 2016 Oct 6;167(2):457-470.e13. doi: 10.1016/j.cell.2016.08.064. Epub 2016 Sep 22. Cell. 2016. PMID: 27667687 Free PMC article.

2

Mitochondria-derived reactive oxygen species mediate blue light-induced death of retinal pigment epithelial cells.

King A, Gottlieb E, Brooks DG, Murphy MP, Dunaief JL. King A, et al. Among authors: gottlieb e. Photochem Photobiol. 2004 May;79(5):470-5. doi: 10.1562/le-03-17.1. Photochem Photobiol. 2004. PMID: 15191057

3

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase.

Selak MA, Armour SM, MacKenzie ED, Boulahbel H, Watson DG, Mansfield KD, Pan Y, Simon MC, Thompson CB, Gottlieb E. Selak MA, et al. Among authors: gottlieb e. Cancer Cell. 2005 Jan;7(1):77-85. doi: 10.1016/j.ccr.2004.11.022. Cancer Cell. 2005. PMID: 15652751 Free article.

4

Redox stress is not essential for the pseudo-hypoxic phenotype of succinate dehydrogenase deficient cells.

Selak MA, Durán RV, Gottlieb E. Selak MA, et al. Among authors: gottlieb e. Biochim Biophys Acta. 2006 May-Jun;1757(5-6):567-72. doi: 10.1016/j.bbabio.2006.05.015. Epub 2006 May 17. Biochim Biophys Acta. 2006. PMID: 16797480 Free article.

5

TIGAR, a p53-inducible regulator of glycolysis and apoptosis.

Bensaad K, Tsuruta A, Selak MA, Vidal MN, Nakano K, Bartrons R, Gottlieb E, Vousden KH. Bensaad K, et al. Among authors: gottlieb e. Cell. 2006 Jul 14;126(1):107-20. doi: 10.1016/j.cell.2006.05.036. Cell. 2006. PMID: 16839880 Free article.

6

Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer.

King A, Selak MA, Gottlieb E. King A, et al. Among authors: gottlieb e. Oncogene. 2006 Aug 7;25(34):4675-82. doi: 10.1038/sj.onc.1209594. Oncogene. 2006. PMID: 16892081 Review.

7

Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells.

MacKenzie ED, Selak MA, Tennant DA, Payne LJ, Crosby S, Frederiksen CM, Watson DG, Gottlieb E. MacKenzie ED, et al. Among authors: gottlieb e. Mol Cell Biol. 2007 May;27(9):3282-9. doi: 10.1128/MCB.01927-06. Epub 2007 Feb 26. Mol Cell Biol. 2007. PMID: 17325041 Free PMC article.

8

Mitochondria in cancer: not just innocent bystanders.

Frezza C, Gottlieb E. Frezza C, et al. Among authors: gottlieb e. Semin Cancer Biol. 2009 Feb;19(1):4-11. doi: 10.1016/j.semcancer.2008.11.008. Epub 2008 Dec 3. Semin Cancer Biol. 2009. PMID: 19101633 Review.

9

Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death.

Tennant DA, Frezza C, MacKenzie ED, Nguyen QD, Zheng L, Selak MA, Roberts DL, Dive C, Watson DG, Aboagye EO, Gottlieb E. Tennant DA, et al. Among authors: gottlieb e. Oncogene. 2009 Nov 12;28(45):4009-21. doi: 10.1038/onc.2009.250. Epub 2009 Aug 31. Oncogene. 2009. PMID: 19718054

10

IDH1 mutations in gliomas: when an enzyme loses its grip.

Frezza C, Tennant DA, Gottlieb E. Frezza C, et al. Among authors: gottlieb e. Cancer Cell. 2010 Jan 19;17(1):7-9. doi: 10.1016/j.ccr.2009.12.031. Cancer Cell. 2010. PMID: 20129244 Free article.

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