Sanchez R - Search Results

1

Convallatoxin-Induced Reduction of Methionine Import Effectively Inhibits Human Cytomegalovirus Infection and Replication.

Cohen T, Williams JD, Opperman TJ, Sanchez R, Lurain NS, Tortorella D. Cohen T, et al. Among authors: sanchez r. J Virol. 2016 Nov 14;90(23):10715-10727. doi: 10.1128/JVI.01050-16. Print 2016 Dec 1. J Virol. 2016. PMID: 27654292 Free PMC article.

2

Suramin inhibits cullin-RING E3 ubiquitin ligases.

Wu K, Chong RA, Yu Q, Bai J, Spratt DE, Ching K, Lee C, Miao H, Tappin I, Hurwitz J, Zheng N, Shaw GS, Sun Y, Felsenfeld DP, Sanchez R, Zheng JN, Pan ZQ. Wu K, et al. Among authors: sanchez r. Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):E2011-8. doi: 10.1073/pnas.1601089113. Epub 2016 Mar 21. Proc Natl Acad Sci U S A. 2016. PMID: 27001857 Free PMC article.

3

Structure-Activity Relationships and Biological Evaluation of 7-Substituted Harmine Analogs for Human β-Cell Proliferation.

Kumar K, Wang P, A Swartz E, Khamrui S, Secor C, B Lazarus M, Sanchez R, F Stewart A, DeVita RJ. Kumar K, et al. Among authors: sanchez r. Molecules. 2020 Apr 23;25(8):1983. doi: 10.3390/molecules25081983. Molecules. 2020. PMID: 32340326 Free PMC article.

4

Privileged diazepine compounds and their emergence as bromodomain inhibitors.

Smith SG, Sanchez R, Zhou MM. Smith SG, et al. Among authors: sanchez r. Chem Biol. 2014 May 22;21(5):573-83. doi: 10.1016/j.chembiol.2014.03.004. Epub 2014 Apr 17. Chem Biol. 2014. PMID: 24746559 Free PMC article. Review.

5

The bromodomain: from epigenome reader to druggable target.

Sanchez R, Meslamani J, Zhou MM. Sanchez R, et al. Biochim Biophys Acta. 2014 Aug;1839(8):676-85. doi: 10.1016/j.bbagrm.2014.03.011. Epub 2014 Mar 28. Biochim Biophys Acta. 2014. PMID: 24686119 Free PMC article. Review.

6

Scaling the druggability landscape of human bromodomains, a new class of drug targets.

Zhang G, Sanchez R, Zhou MM. Zhang G, et al. Among authors: sanchez r. J Med Chem. 2012 Sep 13;55(17):7342-5. doi: 10.1021/jm3011977. Epub 2012 Aug 28. J Med Chem. 2012. PMID: 22928775 Free PMC article. No abstract available.

7

A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication.

Wang P, Alvarez-Perez JC, Felsenfeld DP, Liu H, Sivendran S, Bender A, Kumar A, Sanchez R, Scott DK, Garcia-Ocaña A, Stewart AF. Wang P, et al. Among authors: sanchez r. Nat Med. 2015 Apr;21(4):383-8. doi: 10.1038/nm.3820. Epub 2015 Mar 9. Nat Med. 2015. PMID: 25751815 Free PMC article.

8

Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure.

Kho C, Lee A, Jeong D, Oh JG, Gorski PA, Fish K, Sanchez R, DeVita RJ, Christensen G, Dahl R, Hajjar RJ. Kho C, et al. Among authors: sanchez r. Nat Commun. 2015 Jun 12;6:7229. doi: 10.1038/ncomms8229. Nat Commun. 2015. PMID: 26068603 Free PMC article.

9

Cell type-specific pharmacological kinase inhibition for cancer chemoprevention.

Deshmukh M, Nakagawa S, Higashi T, Vincek A, Venkatesh A, Ruiz de Galarreta M, Koh AP, Goossens N, Hirschfield H, Bian CB, Fujiwara N, Ono A, Hoshida H, El-Abtah M, Ahmad NB, Lujambio A, Sanchez R, Fuchs BC, Poelstra K, Prakash J, Hoshida Y; Precision Liver Cancer Prevention Consortium. Deshmukh M, et al. Among authors: sanchez r. Nanomedicine. 2018 Feb;14(2):317-325. doi: 10.1016/j.nano.2017.11.004. Epub 2017 Nov 20. Nanomedicine. 2018. PMID: 29157977 Free PMC article.

10

The role of human bromodomains in chromatin biology and gene transcription.

Sanchez R, Zhou MM. Sanchez R, et al. Curr Opin Drug Discov Devel. 2009 Sep;12(5):659-65. Curr Opin Drug Discov Devel. 2009. PMID: 19736624 Free PMC article. Review.

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