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Potent and broad-spectrum antibacterial activity of indole-based bisamidine antibiotics: synthesis and SAR of novel analogs of MBX 1066 and MBX 1090.
Williams JD, Nguyen ST, Gu S, Ding X, Butler MM, Tashjian TF, Opperman TJ, Panchal RG, Bavari S, Peet NP, Moir DT, Bowlin TL. Williams JD, et al. Among authors: opperman tj. Bioorg Med Chem. 2013 Dec 15;21(24):7790-806. doi: 10.1016/j.bmc.2013.10.014. Epub 2013 Oct 25. Bioorg Med Chem. 2013. PMID: 24239389 Free PMC article.
TAOK3 phosphorylates the methylenecyclopropane nucleoside MBX 2168 to its monophosphate.
Komazin-Meredith G, Cardinale SC, Comeau K, Magalhaes KJ, Hartline CB, Williams JD, Opperman TJ, Prichard MN, Bowlin TL. Komazin-Meredith G, et al. Among authors: opperman tj. Antiviral Res. 2015 Jul;119:23-7. doi: 10.1016/j.antiviral.2015.04.001. Epub 2015 Apr 7. Antiviral Res. 2015. PMID: 25857706 Free PMC article.
44 results