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Alkylating Agent-Induced NRF2 Blocks Endoplasmic Reticulum Stress-Mediated Apoptosis via Control of Glutathione Pools and Protein Thiol Homeostasis.
Zanotto-Filho A, Masamsetti VP, Loranc E, Tonapi SS, Gorthi A, Bernard X, Gonçalves RM, Moreira JC, Chen Y, Bishop AJ. Zanotto-Filho A, et al. Among authors: goncalves rm. Mol Cancer Ther. 2016 Dec;15(12):3000-3014. doi: 10.1158/1535-7163.MCT-16-0271. Epub 2016 Sep 16. Mol Cancer Ther. 2016. PMID: 27638861 Free PMC article.
Sorafenib improves alkylating therapy by blocking induced inflammation, invasion and angiogenesis in breast cancer cells.
Zanotto-Filho A, Rajamanickam S, Loranc E, Masamsetti VP, Gorthi A, Romero JC, Tonapi S, Gonçalves RM, Reddick RL, Benavides R, Kuhn J, Chen Y, Bishop AJR. Zanotto-Filho A, et al. Among authors: goncalves rm. Cancer Lett. 2018 Jul 1;425:101-115. doi: 10.1016/j.canlet.2018.03.037. Epub 2018 Mar 30. Cancer Lett. 2018. PMID: 29608984 Free PMC article.
N-acetylcysteine and alpha-lipoic acid improve antioxidant defenses and decrease oxidative stress, inflammation and serum lipid levels in ovariectomized rats via estrogen-independent mechanisms.
Delgobo M, Agnes JP, Gonçalves RM, Dos Santos VW, Parisotto EB, Zamoner A, Zanotto-Filho A. Delgobo M, et al. Among authors: goncalves rm. J Nutr Biochem. 2019 May;67:190-200. doi: 10.1016/j.jnutbio.2019.02.012. Epub 2019 Mar 10. J Nutr Biochem. 2019. PMID: 30951973
Thioredoxin reductase-1 levels are associated with NRF2 pathway activation and tumor recurrence in non-small cell lung cancer.
Delgobo M, Gonçalves RM, Delazeri MA, Falchetti M, Zandoná A, Nascimento das Neves R, Almeida K, Fagundes AC, Gelain DP, Fracasso JI, Macêdo GB, Priori L, Bassani N, Bishop AJR, Forcelini CM, Moreira JCF, Zanotto-Filho A. Delgobo M, et al. Among authors: goncalves rm. Free Radic Biol Med. 2021 Dec;177:58-71. doi: 10.1016/j.freeradbiomed.2021.10.020. Epub 2021 Oct 19. Free Radic Biol Med. 2021. PMID: 34673143
COX-2 promotes mammary adipose tissue inflammation, local estrogen biosynthesis, and carcinogenesis in high-sugar/fat diet treated mice.
Gonçalves RM, Delgobo M, Agnes JP, das Neves RN, Falchetti M, Casagrande T, Garcia APV, Vieira TC, Somensi N, Bruxel MA, Mendes DAGB, Rafacho A, Báfica A, Gelain DP, Moreira JCF, Cassali GD, Bishop AJR, Zanotto-Filho A. Gonçalves RM, et al. Cancer Lett. 2021 Apr 1;502:44-57. doi: 10.1016/j.canlet.2021.01.003. Epub 2021 Jan 9. Cancer Lett. 2021. PMID: 33429006 Free article.
Antioxidants Improve Oxaliplatin-Induced Peripheral Neuropathy in Tumor-Bearing Mice Model: Role of Spinal Cord Oxidative Stress and Inflammation.
Agnes JP, Santos VWD, das Neves RN, Gonçalves RM, Delgobo M, Girardi CS, Lückemeyer DD, Ferreira MA, Macedo-Júnior SJ, Lopes SC, Spiller F, Gelain DP, Moreira JCF, Prediger RD, Ferreira J, Zanotto-Filho A. Agnes JP, et al. Among authors: goncalves rm. J Pain. 2021 Aug;22(8):996-1013. doi: 10.1016/j.jpain.2021.03.142. Epub 2021 Mar 24. J Pain. 2021. PMID: 33774154 Free article.
Efficient identification of novel anti-glioma lead compounds by machine learning models.
Neves BJ, Agnes JP, Gomes MDN, Henriques Donza MR, Gonçalves RM, Delgobo M, Ribeiro de Souza Neto L, Senger MR, Silva-Junior FP, Ferreira SB, Zanotto-Filho A, Andrade CH. Neves BJ, et al. Among authors: goncalves rm. Eur J Med Chem. 2020 Mar 1;189:111981. doi: 10.1016/j.ejmech.2019.111981. Epub 2019 Dec 19. Eur J Med Chem. 2020. PMID: 31978780
149 results