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Page 1
Initiation of antiretroviral therapy before detection of colonic infiltration by HIV reduces viral reservoirs, inflammation and immune activation.
Crowell TA, Fletcher JL, Sereti I, Pinyakorn S, Dewar R, Krebs SJ, Chomchey N, Rerknimitr R, Schuetz A, Michael NL, Phanuphak N, Chomont N, Ananworanich J; RV254/SEARCH010 Study Group. Crowell TA, et al. Among authors: fletcher jl. J Int AIDS Soc. 2016 Sep 15;19(1):21163. doi: 10.7448/IAS.19.1.21163. eCollection 2016. J Int AIDS Soc. 2016. PMID: 27637172 Free PMC article.
Persistent, Albeit Reduced, Chronic Inflammation in Persons Starting Antiretroviral Therapy in Acute HIV Infection.
Sereti I, Krebs SJ, Phanuphak N, Fletcher JL, Slike B, Pinyakorn S, O'Connell RJ, Rupert A, Chomont N, Valcour V, Kim JH, Robb ML, Michael NL, Douek DC, Ananworanich J, Utay NS; RV254/SEARCH 010, RV304/SEARCH 013 and SEARCH 011 protocol teams. Sereti I, et al. Among authors: fletcher jl. Clin Infect Dis. 2017 Jan 15;64(2):124-131. doi: 10.1093/cid/ciw683. Epub 2016 Oct 12. Clin Infect Dis. 2017. PMID: 27737952 Free PMC article.
Long-term antiretroviral therapy initiated in acute HIV infection prevents residual dysfunction of HIV-specific CD8+ T cells.
Takata H, Kakazu JC, Mitchell JL, Kroon E, Colby DJ, Sacdalan C, Bai H, Ehrenberg PK, Geretz A, Buranapraditkun S, Pinyakorn S, Intasan J, Tipsuk S, Suttichom D, Prueksakaew P, Chalermchai T, Chomchey N, Phanuphak N, de Souza M, Michael NL, Robb ML, Haddad EK, Crowell TA, Vasan S, Valcour VG, Douek DC, Thomas R, Rolland M, Chomont N, Ananworanich J, Trautmann L; RV254/SEARCH010, RV304/ SEARCH013, and SEARCH011 study groups. Takata H, et al. EBioMedicine. 2022 Oct;84:104253. doi: 10.1016/j.ebiom.2022.104253. Epub 2022 Sep 8. EBioMedicine. 2022. PMID: 36088683 Free PMC article.
Anogenital HIV RNA in Thai men who have sex with men in Bangkok during acute HIV infection and after randomization to standard vs. intensified antiretroviral regimens.
Phanuphak N, Teeratakulpisarn N, van Griensven F, Chomchey N, Pinyakorn S, Fletcher JL, Trichavaroj R, Pattanachaiwit S, Michael N, Phanuphak P, Kim JH, Ananworanich J; RV254/SEARCH 010 Study Group. Phanuphak N, et al. Among authors: fletcher jl. J Int AIDS Soc. 2015 May 7;18(1):19470. doi: 10.7448/IAS.18.1.19470. eCollection 2015. J Int AIDS Soc. 2015. PMID: 25956171 Free PMC article. Clinical Trial.
Markers of HIV reservoir size and immune activation after treatment in acute HIV infection with and without raltegravir and maraviroc intensification.
Ananworanich J, Chomont N, Fletcher JL, Pinyakorn S, Schuetz A, Sereti I, Rerknimitr R, Dewar R, Kroon E, Vandergeeten C, Trichavaroj R, Chomchey N, Chalermchai T, Michael NL, Kim JH, Phanuphak P, Phanuphak N. Ananworanich J, et al. Among authors: fletcher jl. J Virus Erad. 2015;1(2):116-122. Epub 2015 Apr 1. J Virus Erad. 2015. PMID: 26835516 Free PMC article.
Virologic failure is uncommon after treatment initiation during acute HIV infection.
Crowell TA, Phanuphak N, Pinyakorn S, Kroon E, Fletcher JL, Colby D, Tipsuk S, Karnsomlap P, Laopraynak N, O'Connell RJ, Robb ML, Ananworanich J; RV254SEARCH010 Study Group. Crowell TA, et al. Among authors: fletcher jl. AIDS. 2016 Jul 31;30(12):1943-50. doi: 10.1097/QAD.0000000000001148. AIDS. 2016. PMID: 27163706
Initiation of Antiretroviral Therapy During Acute HIV-1 Infection Leads to a High Rate of Nonreactive HIV Serology.
de Souza MS, Pinyakorn S, Akapirat S, Pattanachaiwit S, Fletcher JL, Chomchey N, Kroon ED, Ubolyam S, Michael NL, Robb ML, Phanuphak P, Kim JH, Phanuphak N, Ananworanich J; RV254/SEARCH010 Study Group. de Souza MS, et al. Among authors: fletcher jl. Clin Infect Dis. 2016 Aug 15;63(4):555-61. doi: 10.1093/cid/ciw365. Epub 2016 Jun 17. Clin Infect Dis. 2016. PMID: 27317797
HIV DNA Set Point is Rapidly Established in Acute HIV Infection and Dramatically Reduced by Early ART.
Ananworanich J, Chomont N, Eller LA, Kroon E, Tovanabutra S, Bose M, Nau M, Fletcher JLK, Tipsuk S, Vandergeeten C, O'Connell RJ, Pinyakorn S, Michael N, Phanuphak N, Robb ML; RV217 and RV254/SEARCH010 study groups. Ananworanich J, et al. EBioMedicine. 2016 Sep;11:68-72. doi: 10.1016/j.ebiom.2016.07.024. Epub 2016 Jul 20. EBioMedicine. 2016. PMID: 27460436 Free PMC article.
Immediate initiation of cART is associated with lower levels of cerebrospinal fluid YKL-40, a marker of microglial activation, in HIV-1 infection.
Peluso MJ, Valcour V, Phanuphak N, Ananworanich J, Fletcher JL, Chalermchai T, Krebs SJ, Robb ML, Hellmuth J, Gisslén M, Zetterberg H, Spudich S; RV254SEARCH 010, RV304SEARCH 013, and SEARCH 011 Study Teams. Peluso MJ, et al. Among authors: fletcher jl. AIDS. 2017 Jan 14;31(2):247-252. doi: 10.1097/QAD.0000000000001314. AIDS. 2017. PMID: 27819802 Free PMC article.
153 results