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Nucleoside Analogue Triphosphates Allosterically Regulate Human Ribonucleotide Reductase and Identify Chemical Determinants That Drive Substrate Specificity.
Biochemistry. 2016 Oct 18;55(41):5884-5896. doi: 10.1021/acs.biochem.6b00594. Epub 2016 Oct 3.
Biochemistry. 2016.
PMID: 27634056
Phylogenetic sequence analysis and functional studies reveal compensatory amino acid substitutions in loop 2 of human ribonucleotide reductase.
Knappenberger AJ, Grandhi S, Sheth R, Ahmad MF, Viswanathan R, Harris ME.
Knappenberger AJ, et al.
J Biol Chem. 2017 Oct 6;292(40):16463-16476. doi: 10.1074/jbc.M117.798769. Epub 2017 Aug 14.
J Biol Chem. 2017.
PMID: 28808063
Free PMC article.
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A Modular RNA Domain That Confers Differential Ligand Specificity.
Knappenberger AJ, Reiss CW, Focht CM, Strobel SA.
Knappenberger AJ, et al.
Biochemistry. 2020 Apr 7;59(13):1361-1366. doi: 10.1021/acs.biochem.0c00117. Epub 2020 Mar 27.
Biochemistry. 2020.
PMID: 32202416
Free PMC article.
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Structures of two aptamers with differing ligand specificity reveal ruggedness in the functional landscape of RNA.
Knappenberger AJ, Reiss CW, Strobel SA.
Knappenberger AJ, et al.
Elife. 2018 Jun 7;7:e36381. doi: 10.7554/eLife.36381.
Elife. 2018.
PMID: 29877798
Free PMC article.
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