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DNA methylation changes measured in pre-diagnostic peripheral blood samples are associated with smoking and lung cancer risk.
Baglietto L, Ponzi E, Haycock P, Hodge A, Bianca Assumma M, Jung CH, Chung J, Fasanelli F, Guida F, Campanella G, Chadeau-Hyam M, Grankvist K, Johansson M, Ala U, Provero P, Wong EM, Joo J, English DR, Kazmi N, Lund E, Faltus C, Kaaks R, Risch A, Barrdahl M, Sandanger TM, Southey MC, Giles GG, Johansson M, Vineis P, Polidoro S, Relton CL, Severi G. Baglietto L, et al. Among authors: polidoro s. Int J Cancer. 2017 Jan 1;140(1):50-61. doi: 10.1002/ijc.30431. Epub 2016 Oct 11. Int J Cancer. 2017. PMID: 27632354 Free PMC article.
Dynamics of smoking-induced genome-wide methylation changes with time since smoking cessation.
Guida F, Sandanger TM, Castagné R, Campanella G, Polidoro S, Palli D, Krogh V, Tumino R, Sacerdote C, Panico S, Severi G, Kyrtopoulos SA, Georgiadis P, Vermeulen RC, Lund E, Vineis P, Chadeau-Hyam M. Guida F, et al. Among authors: polidoro s. Hum Mol Genet. 2015 Apr 15;24(8):2349-59. doi: 10.1093/hmg/ddu751. Epub 2015 Jan 2. Hum Mol Genet. 2015. PMID: 25556184 Free PMC article.
Hypomethylation of smoking-related genes is associated with future lung cancer in four prospective cohorts.
Fasanelli F, Baglietto L, Ponzi E, Guida F, Campanella G, Johansson M, Grankvist K, Johansson M, Assumma MB, Naccarati A, Chadeau-Hyam M, Ala U, Faltus C, Kaaks R, Risch A, De Stavola B, Hodge A, Giles GG, Southey MC, Relton CL, Haycock PC, Lund E, Polidoro S, Sandanger TM, Severi G, Vineis P. Fasanelli F, et al. Among authors: polidoro s. Nat Commun. 2015 Dec 15;6:10192. doi: 10.1038/ncomms10192. Nat Commun. 2015. PMID: 26667048 Free PMC article.
DNA methylome analysis identifies accelerated epigenetic ageing associated with postmenopausal breast cancer susceptibility.
Ambatipudi S, Horvath S, Perrier F, Cuenin C, Hernandez-Vargas H, Le Calvez-Kelm F, Durand G, Byrnes G, Ferrari P, Bouaoun L, Sklias A, Chajes V, Overvad K, Severi G, Baglietto L, Clavel-Chapelon F, Kaaks R, Barrdahl M, Boeing H, Trichopoulou A, Lagiou P, Naska A, Masala G, Agnoli C, Polidoro S, Tumino R, Panico S, Dollé M, Peeters PHM, Onland-Moret NC, Sandanger TM, Nøst TH, Weiderpass E, Quirós JR, Agudo A, Rodriguez-Barranco M, Huerta Castaño JM, Barricarte A, Fernández AM, Travis RC, Vineis P, Muller DC, Riboli E, Gunter M, Romieu I, Herceg Z. Ambatipudi S, et al. Among authors: polidoro s. Eur J Cancer. 2017 Apr;75:299-307. doi: 10.1016/j.ejca.2017.01.014. Epub 2017 Feb 28. Eur J Cancer. 2017. PMID: 28259012 Free PMC article. Clinical Trial.
Blood DNA methylation and breast cancer risk: a meta-analysis of four prospective cohort studies.
Bodelon C, Ambatipudi S, Dugué PA, Johansson A, Sampson JN, Hicks B, Karlins E, Hutchinson A, Cuenin C, Chajès V, Southey MC, Romieu I, Giles GG, English D, Polidoro S, Assumma M, Baglietto L, Vineis P, Severi G, Herceg Z, Flanagan JM, Milne RL, Garcia-Closas M. Bodelon C, et al. Among authors: polidoro s. Breast Cancer Res. 2019 May 17;21(1):62. doi: 10.1186/s13058-019-1145-9. Breast Cancer Res. 2019. PMID: 31101124 Free PMC article.
Stochastic Epigenetic Mutations Are Associated with Risk of Breast Cancer, Lung Cancer, and Mature B-cell Neoplasms.
Gagliardi A, Dugué PA, Nøst TH, Southey MC, Buchanan DD, Schmidt DF, Makalic E, Hodge AM, English DR, Doo NW, Hopper JL, Severi G, Baglietto L, Naccarati A, Tarallo S, Pace L, Krogh V, Palli D, Panico S, Sacerdote C, Tumino R, Lund E, Giles GG, Pardini B, Sandanger TM, Milne RL, Vineis P, Polidoro S, Fiorito G. Gagliardi A, et al. Among authors: polidoro s. Cancer Epidemiol Biomarkers Prev. 2020 Oct;29(10):2026-2037. doi: 10.1158/1055-9965.EPI-20-0451. Epub 2020 Aug 11. Cancer Epidemiol Biomarkers Prev. 2020. PMID: 32788174
Agnostic Cys34-albumin adductomics and DNA methylation: Implication of N-acetylcysteine in lung carcinogenesis years before diagnosis.
Dagnino S, Bodinier B, Grigoryan H, Rappaport SM, Karimi M, Guida F, Polidoro S, Edmands WB, Naccarati A, Fiorito G, Sacerdote C, Krogh V, Vermeulen R, Vineis P, Chadeau-Hyam M. Dagnino S, et al. Among authors: polidoro s. Int J Cancer. 2020 Jun 15;146(12):3294-3303. doi: 10.1002/ijc.32680. Epub 2019 Oct 31. Int J Cancer. 2020. PMID: 31513294 Free article.
Appraising the causal relevance of DNA methylation for risk of lung cancer.
Battram T, Richmond RC, Baglietto L, Haycock PC, Perduca V, Bojesen SE, Gaunt TR, Hemani G, Guida F, Carreras-Torres R, Hung R, Amos CI, Freeman JR, Sandanger TM, Nøst TH, Nordestgaard BG, Teschendorff AE, Polidoro S, Vineis P, Severi G, Hodge AM, Giles GG, Grankvist K, Johansson MB, Johansson M, Davey Smith G, Relton CL. Battram T, et al. Among authors: polidoro s. Int J Epidemiol. 2019 Oct 1;48(5):1493-1504. doi: 10.1093/ije/dyz190. Int J Epidemiol. 2019. PMID: 31549173 Free PMC article.
Epigenetic mechanisms of lung carcinogenesis involve differentially methylated CpG sites beyond those associated with smoking.
Petrovic D, Bodinier B, Dagnino S, Whitaker M, Karimi M, Campanella G, Haugdahl Nøst T, Polidoro S, Palli D, Krogh V, Tumino R, Sacerdote C, Panico S, Lund E, Dugué PA, Giles GG, Severi G, Southey M, Vineis P, Stringhini S, Bochud M, Sandanger TM, Vermeulen RCH, Guida F, Chadeau-Hyam M. Petrovic D, et al. Among authors: polidoro s. Eur J Epidemiol. 2022 Jun;37(6):629-640. doi: 10.1007/s10654-022-00877-2. Epub 2022 May 20. Eur J Epidemiol. 2022. PMID: 35595947 Free PMC article.
Methylation-based markers of aging and lifestyle-related factors and risk of breast cancer: a pooled analysis of four prospective studies.
Dugué PA, Bodelon C, Chung FF, Brewer HR, Ambatipudi S, Sampson JN, Cuenin C, Chajès V, Romieu I, Fiorito G, Sacerdote C, Krogh V, Panico S, Tumino R, Vineis P, Polidoro S, Baglietto L, English D, Severi G, Giles GG, Milne RL, Herceg Z, Garcia-Closas M, Flanagan JM, Southey MC. Dugué PA, et al. Among authors: polidoro s. Breast Cancer Res. 2022 Sep 6;24(1):59. doi: 10.1186/s13058-022-01554-8. Breast Cancer Res. 2022. PMID: 36068634 Free PMC article.
121 results